Granted Patent
B2
US 7,812,058 · App. 10/877,781 · Granted Oct 12, 2010
Methods and compounds useful to induce apoptosis in cancer cells
Assignee:
The Burnham Institute
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Abstract
The present invention provides a method for treating cancer in a mammal comprising contacting the cancer cells with a compound which is a apogossypol, derivative.
Claims (7)
1. A method of treating cancer in a mammal, comprising contacting the cancer cells with a compound having the formula (I), or a pharmaceutically acceptable salt thereof:
wherein:
each of R 6 , R 8 , and R 9 are hydroxyl;
R 7 is
each R 10 is methyl,
in the amount effective to reduce the viability of the cancerous cells, thereby treating said cancer,
wherein said cancer is selected from the group consisting of lung cancer, colorectal cancer, breast cancer, and prostate cancer.
Assignments (6)
CONFIRMATORY LICENSE
Recorded Jun 8, 2023
From: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
To: NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR
Reel/Frame 063897/0440 →
CONFIRMATORY LICENSE
Recorded Apr 18, 2023
From: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
To: NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR
Reel/Frame 063357/0380 →
CHANGE OF NAME
Recorded Oct 8, 2020
From: THE BURNHAM INSTITUTE
To: BURNHAM INSTITUTE FOR MEDICAL RESEARCH
Reel/Frame 054030/0487 →
CHANGE OF NAME
Recorded Oct 8, 2020
From: BURNHAM INSTITUTE FOR MEDICAL RESEARCH
To: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
Reel/Frame 054030/0815 →
CHANGE OF NAME
Recorded Oct 8, 2020
From: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
To: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
Reel/Frame 054031/0281 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Mar 6, 2006
From: REED, JOHN C.; PELLECCHIA, MAURIZIO
To: THE BURNHAM INSTITUTE
Reel/Frame 017307/0175 →
Continuity (2)
Provisional Application
6048288600
· Jun 25, 2003