IP Library Granted Patent US 7,812,058
Granted Patent B2
US 7,812,058 · App. 10/877,781 · Granted Oct 12, 2010

Methods and compounds useful to induce apoptosis in cancer cells

Assignee: The Burnham Institute
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Quick Facts
Patent No.
US 7,812,058
App. No.
10/877,781
Granted
Oct 12, 2010
Kind
B2
Abstract

The present invention provides a method for treating cancer in a mammal comprising contacting the cancer cells with a compound which is a apogossypol, derivative.

Claims (7)

1. A method of treating cancer in a mammal, comprising contacting the cancer cells with a compound having the formula (I), or a pharmaceutically acceptable salt thereof:

wherein:

each of R 6 , R 8 , and R 9 are hydroxyl;

R 7 is

each R 10 is methyl,

in the amount effective to reduce the viability of the cancerous cells, thereby treating said cancer,

wherein said cancer is selected from the group consisting of lung cancer, colorectal cancer, breast cancer, and prostate cancer.

Assignments (6)
CONFIRMATORY LICENSE Recorded Jun 8, 2023
From: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
To: NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR
Reel/Frame 063897/0440 →
CONFIRMATORY LICENSE Recorded Apr 18, 2023
From: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
To: NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR
Reel/Frame 063357/0380 →
CHANGE OF NAME Recorded Oct 8, 2020
From: THE BURNHAM INSTITUTE
To: BURNHAM INSTITUTE FOR MEDICAL RESEARCH
Reel/Frame 054030/0487 →
CHANGE OF NAME Recorded Oct 8, 2020
From: BURNHAM INSTITUTE FOR MEDICAL RESEARCH
To: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
Reel/Frame 054030/0815 →
CHANGE OF NAME Recorded Oct 8, 2020
From: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
To: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
Reel/Frame 054031/0281 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 6, 2006
From: REED, JOHN C.; PELLECCHIA, MAURIZIO
To: THE BURNHAM INSTITUTE
Reel/Frame 017307/0175 →
Continuity (2)
Provisional Application 6048288600 · Jun 25, 2003
Related Publication 20050027000A1 · Feb 3, 2005