Methods of treating neurological conditions with hematopoietic growth factors
The present invention relates to a method of treating a neurological condition in a mammal by administering at least one hematopoietic growth factor.
1. A method of treating peripheral neuropathy caused by AIDS or diabetes in a mammal, consisting of administering to the mammal which is suffering from peripheral neuropathy caused by AIDS or diabetes, mammalian G-CSF, human G-CSF, a protein having at least 90% homology to SEQ ID NO:37 and G-CSF activity, a protein having at least 90% homology to SEQ ID NO:38 and G-CSF activity, a protein having at least 90% homology to SEQ ID NO:39 and G-CSF activity, PEG-modified G-CSF, or a combination thereof with a pharmaceutically acceptable carrier, in an amount sufficient to treat the peripheral neuropathy in said mammal.
2. The method of claim 1 , wherein the mammal is human.
3. The method of claim 1 , wherein a human G-CSF is administered.
4. The method of claim 1 , wherein a protein having at least 90% homology to SEQ ID NO:37, SEQ ID NO:38 or SEQ ID NO:39 and which has G-CSF activity is administered.
5. The method of claim 4 , wherein a protein having at least 95% homology to SEQ ID NO:37, SEQ ID NO:38 or SEQ ID NO:39 and which has G-CSF activity is administered.
6. The method of claim 1 , wherein human or mammalian PEG-modified G-CSF is administered.