Salts of 4- or 5-aminosalicylic acid
The present invention provides L-arginine salts of 4- or 5-aminosalicylic acid, and a pharmaceutical composition containing these L-arginine salts of 4- or 5-aminosalicylic acid as active ingredients, useful for the treatment of an inflammatory condition of the GI tract such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS).
1. The L-arginine salt of 4-aminosalicylic acid.
2. The L-arginine salt of 5-aminosalicylic acid.
3. A pharmaceutical composition comprising a compound according to claim 1 or claim 2 and a pharmaceutically acceptable excipient or carrier.
4. A method of treating an inflammatory condition of the gastrointestinal tract in a subject in need of such treatment, said method comprising administering to the subject an amount effective to treat the inflammatory condition of the gastrointestinal tract of a compound according to claim 1 or claim 2 .
5. The method according to claim 4 , wherein the inflammatory condition of the gastrointestinal tract is Crohn's disease.
6. The method according to claim 4 , wherein the inflammatory condition of the gastrointestinal tract is ulcerative colitis.
7. The method according to claim 4 , wherein the inflammatory condition of the gastrointestinal tract is irritable bowel syndrome.