Methods and compositions for the treatment and prevention of tumors, tumor-related disorders and cachexia
Certain cyclooxygenase-2 inhibitors are useful for the treatment and prevention of tumors and tumor-related disorders and cachexia.
1. A method for inhibiting tumor growth in a mammal in need thereof, which method comprises administering to said mammal an effective amount of an active compound selected from the group consisting of 2-(4-ethoxyphenyl)-4-methyl-1-(4sulfamoylphenyl)pyrrole and pharmaceutically acceptable salts thereof.
2. A method for inhibiting tumor metastasis in a mammal in need thereof, which method comprises administering to said mammal an effective amount of an active compound selected from the group consisting of 2-(4-ethoxyphenyl)-4-methyl-1-(4sulfamoylphenyl)pyrrole and pharmaceutically acceptable salts thereof.
3. The method of claim 1 comprising administering to said mammal an effective amount of 2-(4-ethoxyphenyl)-4-methyl-1-(4sulfamoylphenyl)pyrrole.
4. The method of claim 1 comprising administering to said mammal a pharmaceutically acceptable salt of 2-(4-ethoxyphenyl)-4-methyl-1-(4sulfamoylphenyl)pyrrole.
5. The method of claim 2 comprising administering to said mammal an effective amount of 2-(4-ethoxyphenyl)-4-methyl-1-(4sulfamoylphenyl)pyrrole.
6. The method of claim 2 comprising administering to said mammal a pharmaceutically acceptable salt of 2-(4-ethoxyphenyl)-4-methyl-1-(4sulfamoylphenyl)pyrrole.