Granted Patent
B2
US 7,238,372 · App. 10/918,762 · Granted Jul 3, 2007
Methods for inhibiting tumor cell proliferation
Assignee:
University of South Florida
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Abstract
The subject invention concerns methods for inhibition of STAT biological functions using platinum complexes.
Claims (5)
1. A method for inhibiting a Stat3 transcription factor comprising contacting a tumor cell, cancer cell or transformed cell expressing a Stat3 transcription factor with the platinum complex:
or a pharmaceutically-acceptable salt thereof.
2. The method according to claim 1 , wherein said cell is a mammalian cell.
3. The method according to claim 2 , wherein said mammalian cell is a human cell, monkey cell, chimpanzee cell, ape cell, dog cell, cat cell, horse cell, cow cell, or pig cell.
4. The method according to claim 1 , wherein said platinum complex is encapsulated in a liposome moiety.
Assignments (2)
CONFIRMATORY LICENSE
Recorded Jun 20, 2017
From: UNIVERSITY OF SOUTH FLORIDA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 042903/0241 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Dec 9, 2004
From: TURKSON, JAMES; JOVE, RICHARD; PALMER, JAY W.; KAY, HEIDI; YU, HUA
To: SOUTH FLORIDA, UNIVERSITY OF
Reel/Frame 015440/0307 →
Continuity (5)
Provisional Application
6052529500
· Nov 25, 2003
Provisional Application
6051994300
· Nov 14, 2003
Provisional Application
6051558000
· Oct 30, 2003
Provisional Application
6048122600
· Aug 13, 2003