Artificial bone and joint compositions
View Patent ↗The present invention provides a ceramic porous body for in-vitro and in-vivo use comprising a composition comprising a calcium aluminate (CA) containing phase and optionally at least one of an accelerator, a retarder, a surfactant, a foaming agent, a reactive alumina, water, a fiber, and a biologically active material, and combinations thereof. Ceramic compositions are provides as well as method of using the ceramic compositions and methods of manufacturing a ceramic porous body. The ceramic porous bodies of this invention may be used as artificial bones, joints, in-vitro support structures, and in-vivo support structures for cells, tissues, organs, and nerve growth and regeneration.
1. A porous ceramic body for in vitro and in vivo use consisting essentially of a fired nonhydratable composition consisting essentially of;
a calcium aluminate (CA) containing phase that is a single nonhydratable CA 6 phase, and a biologically active material that comprises at least one or more proteins for promoting bone growth, and a fiber, said CA 6 phase, said biologically active material and said fiber forming a ceramic body having interconnected porosity and that is chemically compatible with natural bone.
2. The porous ceramic body of claim 1 having a porosity suitable for achieving vascularity.
3. The porous ceramic body of claim 1 wherein said composition is capable of being functionalized for use with biologic processes.
4. The porous ceramic body of claim 3 wherein said biological processes include accommodation of binding sites.
5. The porous ceramic body of claim 1 wherein said composition is capable of being used to repair a bone void of a patient.
6. The porous ceramic body of claim 1 that is selected from the group consisting of an artificial bone, artificial joint, in-vitro support structure, and in-vivo support structure.
7. The porous ceramic body of claim 6 wherein said in-vitro and in-vivo support structures are a scaffold matrix for support of cell, tissue, organ and nerve growth.