IP Library › Granted Patent US 7,236,813
Granted Patent B2
US 7,236,813 · App. 10/994,682 · Granted Jun 26, 2007

Optical device

Assignee: Edwards Lifesciences Corporation
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Quick Facts
Patent No.
US 7,236,813
App. No.
10/994,682
Granted
Jun 26, 2007
Kind
B2
Abstract

A method for monitoring blood oxygen saturation (SO 2 ) includes the steps of calculating an estimate of SO 2 in the blood and correcting the estimate by a scaling factor. A preferred embodiment of the method includes the steps of transmitting light containing a plurality of wavelengths into the blood; measuring a remitted spectrum over the plurality of wavelengths; calculating a measured blood absorption spectrum from the remitted spectrum; estimating local rates of change in the measured blood absorption spectrum at a plurality of the wavelengths; and calculating the estimate of SO 2 as a function of absolute values of the local rates of change of the measured blood absorption spectrum.

Claims (18)

1. A method for SO 2 monitoring, comprising the steps of:

calculating an estimate of SO 2 in blood to be monitored;

correcting said estimate of SO 2 in blood by a scaling factor;

transmitting light containing a plurality of wavelengths into the blood;

measuring a remitted spectrum over the plurality of wavelengths;

calculating a measured blood absorption spectrum from the remitted spectrum;

estimating local rates of change in the measured blood absorption spectrum at a plurality of the wavelengths, including at least one isobestic wavelength; and,

calculating the estimate of SO 2 as a function of absolute values of the local rates of change of the measured blood absorption spectrum.

2. The method for SO 2 monitoring according to claim 1 , wherein before said step of calculating the estimate of SO 2, further comprising the steps of:

removing effects of light scattering from the measured blood absorption spectrum;

calculating an area under the measured blood absorption spectrum after said step of removing effects of light scattering; and,

normalizing the measured blood absorption spectrum by the area under the measured blood absorption spectrum determined during said step of calculating.

3. The method for SO 2 monitoring according to claim 1 , further comprising the step of applying a Kubelka Monk transformation to the measured blood absorption spectrum.

4. The method for SO 2 monitoring according to claim 1 , wherein the step of calculating the estimate of SO 2 comprises the steps of:

computing a hemoglobin index value as a function of absolute values of the local rates of change of the measured blood absorption spectrum between a plurality of pairs of isobestic points, whereby the hemoglobin index value is independent of blood oxygenation;

computing an oxygenation parameter as a function of absolute values of the local rates of change of the measured blood absorption spectrum between a plurality of isobestic points and at least one non-isobestic point, whereby the oxygenation parameter is dependent on blood oxygenation;

normalizing the oxygenation parameter by the hemoglobin index value; and,

estimating SO 2 as a measure of the level of the normalized oxygenation parameter relative to a predetermined fully deoxygenated reference value and a fully oxygenated reference value.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 29, 2010
From: PARKER, DAWOOD
To: WHITLAND RESEARCH LIMITED
Reel/Frame 024309/0527 →
Priority Claims (2)
GB 9817552.4 · Aug 13, 1998 · national
GB 9904232.7 · Feb 25, 1999 · national
Continuity (2)
Division 0976292300
Related Publication 20050101850A1 · May 12, 2005