IP Library › Granted Patent US 7,655,668
Granted Patent B1
US 7,655,668 · App. 11/037,403 · Granted Feb 2, 2010

Composition and method for treatment of warts

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Quick Facts
Patent No.
US 7,655,668
App. No.
11/037,403
Granted
Feb 2, 2010
Kind
B1
Abstract

Provided is a composition that includes 5-FU and salicylic acid. This composition is useful as a treatment for warts. As opposed to conventional compositions and methods, this composition need only be applied once a day. Also provided are methods for the preparation and use of the composition for treatment of warts.

Claims (5)

1. A composition for treatment of warts consisting of: from 0.5 to 5.0% by weight 5-fluorouracil (5-FU); from 10.0 to 25.0% by weight salicylic acid; from 5 to 50% by weight of DMSO; from 1-10% by weight of a water-swellable polymer; and from 10-75% by weight of an adhesive; whereby the composition is a sustained release topical gel that releases salicylic acid onto the wart for removal of keratin of the wart and surrounding skin to allow penetration of the 5-FU into the wart.

2. A composition for treatment of warts consisting of: from 0.5 to 5.0% by weight 5-fluorouracil (5-FU); from 10.0 to 25.0% by weight salicylic acid; from 5 to 50% by weight of DMSO; from 1-10% by weight of a water-swellable polymer; and 10-75% by weight of an adhesive; whereby the composition is a sustained release topical gel that releases salicylic acid onto the wart for removal of keratin of the wart and surrounding skin to allow penetration of the 5-FU into the wart.

3. A composition for treatment of warts consisting of: from 0.5 to 5.0% by weight 5-fluorouracil (5-FU); from 10.0 to 25.0% by weight salicylic acid; from 5 to 50% by weight DMSO; from 0.4 to 2.0% by weight lecithin; from 1-10% by weight of a water-swellable polymer; and 10-75% polyvinyl alcohol gel that releases salicylic acid onto the wart for removal of keratin of the wart and surrounding skin to allow penetration of the 5-FU into the wart.

4. A composition for treatment of warts consisting of: 2% by weight 5-fluorouracil (5-FU); 17% by weight salicylic acid; from about 5 to 50% by weight of DMSO; from about 1-10% by weight of a water-swellable polymer; and 10-75% by weight of an adhesive; whereby the composition is a sustained release topical gel that releases salicylic acid onto the wart for removal of keratin of the wait and surrounding skin to allow penetration of the 5-FU into the wart.

5. A composition for treatment of warts consisting of: from 2-5% by weight 5-fluorouracil (5-FU); from 10-25% by weight salicylic acid; from 5 to 50% by weight of DMSO; from 1-10% by weight of a water-swellable polymer; and 10-75% by weight of an adhesive; whereby the composition is a sustained release topical gel that releases salicylic acid onto the wart for removal of keratin of the wart and surrounding skin to allow penetration of the 5-FU into the wart.

Assignments (3)
CORRECTIVE ASSIGNMENT TO CORRECT THE PATENT APPLICATION NUMBER FROM 11137403 TO 11037403 PREVIOUSLY RECORDED ON REEL 023218 FRAME 0098. ASSIGNOR(S) HEREBY CONFIRMS THE CHANGE OF NAME OF PATENT APPLICATION SERIAL NOS. 11037403, 11094978, AND 11369638 TO MEDCARA, L.L.C.. Recorded May 14, 2010
From: NUCARA PHARMACEUTICAL, L.C.
To: MEDCARA, L.L.C.
Reel/Frame 024388/0127 →
CHANGE OF NAME Recorded Sep 11, 2009
From: NUCARA PHARMACEUTICAL, L.C.
To: MEDCARA, L.L.C.
Reel/Frame 023218/0098 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 18, 2005
From: HERMAN, CRAIG
To: NUCARA PHARMACEUTICAL, LLC
Reel/Frame 015792/0870 →