Iontophoretic drug delivery device and reservoir and method of making same
A reservoir electrode assembly of the present invention for an iontophoretic drug delivery device includes an electrode and a hydrophilic reservoir situated in electrically conductive relation to the electrode. The hydrophilic reservoir is formed from a bibulous hydrophilic cross-linked polymeric material having a first surface and a second surface that is adhesively adherent to the electrode. The first surface of the polymeric material is releasably adhesively adherent when applied to an area of a patient's skin. The polymeric material has a cohesive strength forms an adhesive bond with a bond strength between the second surface of the polymeric material to the electrode that is greater than the cohesive strength of the polymeric material. Additionally, an adhesive bond strength of the first surface of the polymeric material to the applied area of the patient is less than the cohesive strength of the polymeric material so that upon removal of the reservoir assembly of the invention from the applied area of the patient, substantially no polymeric material remains on the applied area and the hydrophilic reservoir remains substantially intact and adhesively adherent to the electrode.
1 - 40 . (canceled)
41 . An iontophoretic drug delivery device, comprising:
an electrode assembly, comprising:
a reservoir situated in electrically conductive relation to the electrode assembly, wherein the reservoir comprises an aqueous swollen high energy irradiation cross-linked water soluble polymer.
42 . The iontophoretic drug delivery device of claim 41 , wherein the aqueous swollen high energy irradiation cross-linked water soluble polymer is crosslinked by exposure to electron beam irradiation or gamma irradiation.
43 . The iontophoretic drug delivery device of claim 41 , wherein the reservoir further comprises at least one medicament.
44 . The iontophoretic drug delivery device of claim 42 , wherein the aqueous swollen high energy irradiation cross linked water soluble polymer is selected from polyethylene oxide, polyvinyl pyrrolidone, polyvinyl alcohol, and polyacrylimide.
45 - 70 . (canceled)