IP Library Granted Patent US 7,705,049
Granted Patent B2
US 7,705,049 · App. 11/044,638 · Granted Apr 27, 2010

Methods for treating non-melanoma cancers with PABA

Assignee: New York University
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Quick Facts
Patent No.
US 7,705,049
App. No.
11/044,638
Granted
Apr 27, 2010
Kind
B2
Abstract

The present invention relates to a method for treating non-melanotic cancers by administration of PABA. The present invention also relates to the potentiation of standard cancer treatment of radiation, radioimmunotherapy, and/or chemotherapy using PABA.

Claims (3)

1. A method of treating non-melanotic cancer in a subject in need of such treatment comprising orally administering to the subject an effective amount of para-aminobenzoic acid (PABA) in combination with at least one of radiotherapy, radioimmunotherapy, or a chemotherapeutic agent selected from the group consisting of paclitaxel, docetaxel, carboplatin, vinorelbine, and gemcitabine; wherein the non-melanotic cancer is breast cancer.

2. A method of treating non-melanotic cancer in a subject in need of such treatment comprising orally administering to the subject an effective amount of para-aminobenzoic acid (PABA) in combination with at least one of radiotherapy, radioimmunotherapy, or a chemotherapeutic agent selected from the group consisting of paclitaxel, docetaxel, carboplatin, vinorelbine, and gemcitabine; wherein the non-melanotic cancer is non-small cell lung carcinoma.

3. A method of inhibiting metastasis of tumor cells comprising contacting the tumor cells with an effective amount of PABA in combination with chemotherapy, wherein the tumor cells are breast tumor cells and the chemotherapy is paclitaxel.

Assignments (3)
CONFIRMATORY LICENSE Recorded Oct 3, 2022
From: NEW YORK UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR
Reel/Frame 061285/0608 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 28, 2009
From: MORAIS, DANIELLE
To: NEW YORK UNIVERSITY
Reel/Frame 023161/0591 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 15, 2005
From: BROOKS, PETER C.; LIEBES, LEONARD; KRAMER, ELISSA; NG, BRUCE
To: NEW YORK UNIVERSITY
Reel/Frame 016707/0671 →
Continuity (2)
Provisional Application 6053835900 · Jan 21, 2004
Related Publication 20050220705A1 · Oct 6, 2005