Nematode PPPT-like sequences
Disclosed are a nucleic acid molecule from nematodes encoding for purine/pyrimidine phosphoribosyl transferase (PPPT) polypeptides. The PPPT-like polypeptide sequence is also provided, as are vectors, host cells, and recombinant methods for production of PPPT-like nucleotides and polypeptides. The invention further relates to screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
1 - 4 . (canceled)
5 . An isolated nucleic acid molecule comprising a nucleotide sequence encoding a polypeptide comprising the amino acid sequence of SEQ ID NO: 4.
6 . The isolated nucleic acid molecule of claim 5 comprising the nucleotide sequence of SEQ ID NO:7.
7 . The isolated nucleic acid molecule of claim 6 , further comprising an operably linked heterologous promoter.
8 - 13 . (canceled)
14 . The isolated nucleic acid molecule of claim 5 wherein the polypeptide consists of the amino acid sequence of SEQ ID NO: 4.