Canine CD20 compositions
The invention provides canine CD20 nucleotide and protein sequences. These compositions are useful in the diagnosis and treatment of, e.g., CD20+ B-cell lymphoma, immune-mediated hemolytic anemia, immune-mediated thrombocytopenia, and systemic lupus erythematosus (SLE) in canines and felines.
1. An isolated canine CD20 protein comprising the amino acid sequence shown in SEQ ID NO: 6.
2. The isolated protein of claim 1 , wherein the protein is present in a fusion protein.
3. An isolated polypeptide comprising the amino acid sequence shown in SEQ ID NO: 10.
4. The isolated polypeptide of claim 3 , wherein the polypeptide is present in a fusion protein.
5. An isolated polypeptide, wherein the polypeptide comprises the amino acid sequence shown in SEQ ID NO: 11.