IP Library Granted Patent US 8,821,559
Granted Patent B2
US 8,821,559 · App. 11/214,445 · Granted Sep 2, 2014

Light-based implants for treating Alzheimer's disease

Inventors: Thomas DiMauro (Southboro, MA); Mohamed Attawia (Canton, MA); Sean Lilienfeld (Sharon, MA); Chantal Holy (Raynham, MA); Jeffrey K Sutton (Medway, MA); Michael Ward (Providence, RI)
Assignee: Codman & Shurtleff, Inc.
A61N5/0601A61N2005/0661A61N2005/0651A61N2005/0659A61N2005/063
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Quick Facts
Patent No.
US 8,821,559
App. No.
11/214,445
Granted
Sep 2, 2014
Kind
B2
Abstract

An intracranial, light-emitting implant for providing therapy to a patient having Alzheimer's Disease.

Claims (14)

1. A method of treating a patient having Alzheimer's Disease, comprising the steps of:

a) providing a device comprising an LED and a fiber optic cable having a proximal end portion and a distal end portion;

b) implanting the device into the patient so that the distal end portion of the fiber optic cable is located adjacent to the hippocampus, and

c) delivering light provided in a wavelength of between 600 nm and about 1000 nm from the LED through the proximal end portion of the fiber optic cable to the distal end portion of the cable, and

d) irradiating the hippocampus with an effective amount of the delivered light,

wherein the fiber optic cable and LED are located inside the patient's skull,

wherein the distal end portion of the fiber optic cable does not directly contact the hippocampus.

2. A method of treating a patient having Alzheimer's Disease, comprising the steps of:

a) providing a device comprising an LED and a fiber optic cable having a proximal end portion and a distal end portion;

b) implanting the device into the patient so that the distal end portion of the fiber optic cable is located adjacent to the hippocampus, and

c) delivering light provided in a wavelength of between 650 nm and about 1000 nm from the LED through the proximal end portion of the fiber optic cable to the distal end portion of the cable, and

d) irradiating the hippocampus with an effective amount of the delivered light,

wherein the fiber optic cable and LED are located inside the patient's skull,

wherein the distal end portion of the fiber optic cable does not directly contact the hippocampus.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 23, 2016
From: HOLY, CHANTAL; SUTTON, JEFFREY K; WARD, MICHAEL
To: DEPUY SYNTHES PRODUCTS, INC.
Reel/Frame 039503/0932 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 18, 2016
From: CODMAN & SHURTLEFF, INC.
To: DEPUY SPINE, LLC
Reel/Frame 039471/0516 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 18, 2016
From: DEPUY SPINE, LLC
To: HAND INNOVATIONS LLC
Reel/Frame 039471/0547 →
CHANGE OF NAME Recorded Aug 18, 2016
From: HAND INNOVATIONS LLC
To: DEPUY SYNTHES PRODUCTS, LLC
Reel/Frame 039723/0882 →
CONVERSION Recorded Aug 18, 2016
From: DEPUY SYNTHES PRODUCTS, LLC
To: DEPUY SYNTHES PRODUCTS, INC.
Reel/Frame 039723/0885 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 25, 2006
From: DIMAURO, THOMAS; MOHAMED, ATTAWIA; LILIENFELD, SEAN
To: CODMAN & SHURTLEFF, INC.
Reel/Frame 017496/0171 →
Continuity (2)
Provisional Application 60661629 · Mar 14, 2005
Related Publication 20060100679A1 · May 11, 2006