Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino] benzonitrile
The present invention relates to a pharmaceutical composition comprising as active ingredient the hydrochloric acid salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethyl-phenyl]amino]-2-pyrimidinyl]amino]benzonitrile and to processes for their preparation.
1. A pharmaceutical composition comprising a pharmaceutically acceptable carrier and a compound of formula (I-a)
wherein said pharmaceutically acceptable carrier comprises:
from 0.01 to 5% of said pharmaceutical composition of a wetting agent;
from 40 to 92% of said pharmaceutical composition of a diluent;
from 0 to 10% of said pharmaceutical composition of a polymer;
from 2 to 10% of said pharmaceutical composition of a disintegrant;
from 0.1 to 5% of said pharmaceutical composition of a glidant; and
from 0.1 to 1.5% of said pharmaceutical composition of a lubricant;
and wherein said compound of formula (I-a) is present in said pharmaceutical composition at from 5-50% of said pharmaceutical composition.