Method of delaying ejaculation
The invention provides a method of delaying ejaculation. The method comprises administering an effective amount of a tramadol material to a human male prior to sexual intercourse. The method is particularly useful for treating premature ejaculation.
1 . A method of delaying ejaculation comprising administering an effective amount of a tramadol material to a human male prior to sexual intercourse.
2 . The method of claim 1 wherein the tramadol material is tramadol or a pharmaceutically-acceptable salt thereof.
3 . The method of claim 2 wherein the tramadol material is (±) cis-tramadol or a pharmaceutically-acceptable salt thereof.
4 . The method of claim 3 wherein a dose of from about 10 to about 50 milligrams of the tramadol or the pharmaceutically-acceptable salt thereof is administered to the male.
5 . The method of claim 4 wherein a dose of from about 15 to about 35 milligrams of the tramadol or the pharmaceutically-acceptable salt thereof is administered to the male.
6 . The method of claim 5 wherein a dose of about 25 milligrams of the tramadol or the pharmaceutically-acceptable salt thereof is administered to the male.
7 . The method of claim 3 wherein a (+)-enantiomer of the cis-tramadol or the pharmaceutically-acceptable salt thereof is administered to the male.
8 . The method of claim 3 wherein a (−)-enantiomer of the cis-tramadol or the pharmaceutically-acceptable salt thereof is administered to the male.
9 . The method of claim 3 wherein the tramadol material is (±) cis-tramadol hydrochloride.
10 . The method of claim 9 wherein a dose of from about 10 to about 50 milligrams of the tramadol hydrochloride is administered to the male.
11 . The method of claim 10 wherein a dose of from about 15 to about 35 milligrams of the tramadol hydrochloride is administered to the male.
12 . The method of claim 11 wherein a dose of about 25 milligrams of the tramadol hydrochloride is administered to the male.
13 . The method of any one of claims 1 - 12 wherein the tramadol material is administered from about 30 minutes to about 60 minutes prior to sexual intercourse.
14 . The method of any one of claims 1 - 12 wherein the tramadol material is administered orally.
15 . The method of claim 13 wherein the tramadol material is administered orally.
16 . The method of any one of claims 1 - 12 wherein the male suffers from premature ejaculation.
17 . The method of claim 13 wherein the male suffers from premature ejaculation.
18 . The method of claim 14 wherein the male suffers from premature ejaculation.
19 . The method of claim 15 wherein the male suffers from premature ejaculation.