IP Library › Granted Patent US 7,199,267
Granted Patent B1
US 7,199,267 · App. 11/254,743 · Granted Apr 3, 2007

Recognition of oligiosaccaride molecular targets by polycationic small molecule inhibitors and treatment of immunological disorders and infectious diseases

Assignees: MediQuest Therapeutics, Inc.; The University of Kansas
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Quick Facts
Patent No.
US 7,199,267
App. No.
11/254,743
Granted
Apr 3, 2007
Kind
B1
Abstract

Small molecule polycationic agents are used to modulate or interrupt biological processes by binding to oligosaccharide-based biomolecules. Compounds that inhibit nitric oxide, TNFα or other immunomodulators are provided and are useful for treating immunological disease and disease of an infectious disorder.

Claims (11)

1. A compound selected from the group consisting of

and salts thereof.

2. The compound of claim 1 being represented by the formula:

3. The compound of claim 1 being represented by the formula:

4. The compound of claim 1 being represented by the formula:

5. The compound of claim 1 being represented by the formula:

6. A composition comprising a compound according to claim 1 .

7. A composition comprising a compound according to claim 2 .

8. A composition comprising a compound according to claim 3 .

9. A composition comprising a compound according to claim 4 .

10. A composition comprising a compound according to claim 5 .

Assignments (3)
CONFIRMATORY LICENSE Recorded Jul 18, 2018
From: UNIVERSITY OF KANSAS
To: NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR
Reel/Frame 046584/0196 →
CONFIRMATORY LICENSE Recorded Sep 15, 2009
From: UNIVERSITY OF KANSAS LAWRENCE
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 023229/0301 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 15, 2006
From: BURNS, MARK R.; DAVID, SUNIL A.
To: MEDIQUEST THERAPEUTICS, INC.; KANSAS, THE UNIVERSITY OF
Reel/Frame 017301/0123 →