Polymer network compositions and associated methods
View Patent ↗Biomimetic polymer networks comprising a heteropolymer network having a cavity, the cavity having a selective affinity for a moiety, methods for making biomimetic polymer networks, and methods for using biomimetic polymer networks.
1. A biomimetic polymer network comprising a heteropolymer network having a cavity, the cavity having a selective affinity for a moiety, wherein network comprises a copolymer of acrylamide, methacrylamide, ethacrylamide, and isopropyl acrylamide crosslinked with an ethylene glycol dimethacrylate and the moiety comprises glucose.
2. The biomimetic polymer network of claim 1 wherein the cavity and moiety interact through noncovalent binding.
3. The biomimetic polymer network of claim 1 further comprising the moiety.
4. The biomimetic polymer network of claim 1 further comprising the moiety, wherein the moiety is conjugated to a molecule.
5. The biomimetic polymer network of claim 1 further comprising the moiety, wherein the moiety is conjugated to a molecule that is a therapeutic agent, wherein the therapeutic agent comprises hydrocodone.
6. A biomimetic polymer network formed by a process comprising polymerizing a mixture comprising monomers and crosslinkers in the presence of a moiety for which a molecular imprint is to be produced, thereby forming a matrix comprising an imprint of the molecule, and separating the moiety from the matrix, wherein network comprises a copolymer of acrylamide, methacrylamide, ethacrylamide, and isopropyl acrylamide crosslinked with an ethylene glycol dimethacrylate and the moiety comprises glucose.
7. The biomimetic polymer network of claim 6 wherein the mixture comprises a prepolymerization complex, the prepolymerization complex comprising a moiety for which a molecular imprint is to be produced.
8. The biomimetic polymer network of claim 6 wherein the moiety is conjugated to a molecule that is a therapeutic agent, wherein the therapeutic agent comprises hydrocodone.