Antibody against G-protein coupled receptor showing selective affinity for ATP and uses therefor
View Patent ↗The present invention relates to isolated antibodies both polyclonal and monoclonal, that specifically bind to a G-protein coupled receptor showing selective affinity for ATP. The invention further comprises a pharmaceutical composition comprising antibodies that specifically bind to the G-protein coupled receptor showing selective affinity for ATP.
1. An antibody which binds to a polypeptide comprising amino acid residues 424-795 of SEQ ID NO: 1, wherein said antibody binds to an epitope in amino acid residues 424-795 of SEQ ID NO:1.
2. The antibody of claim 1 , wherein said antibody is an antagonist of said polypeptide.
3. The antibody of claim 1 , wherein said antibody is a monoclonal antibody.
4. The antibody of claim 3 , wherein said epitope is present on the surface of a cell expressing said polypeptide.
5. A pharmaceutical composition comprising the antibody of claim 1 , and a pharmaceutically acceptable carrier.