IP Library Granted Patent US 9,498,548
Granted Patent B2
US 9,498,548 · App. 11/416,091 · Granted Nov 22, 2016

Method of using oxidative reductive potential water solution in dental applications

Inventor: Hojabr Alimi (Santa Rosa, CA)
Assignee: Oculus Innovative Sciences, Inc.
A61L2/035A61K33/20A61K33/40A61L2/183A61L2/186A61C1/0076A61L2202/24
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 9,498,548
App. No.
11/416,091
Granted
Nov 22, 2016
Kind
B2
Abstract

Methods of using oxidative reduction potential (ORP) water solution that is stable for at least twenty-four hours in dental applications are provided. The ORP water solution can be administered to patients for the routine disinfection of the oral cavity as part of an on-going program of oral hygiene. The ORP water solution can further be used to irrigate and/or disinfect oral tissues and surfaces during dental procedures, oral surgery, or maxillo-facial surgery. Also, the ORP water solution can be administered to treat patients with damage to the oral tissues caused by disease or surgery.

Claims (10)

1. A method of treating periodontal diseases in a patient comprising administering an oxidative reductive potential water solution to the patient in an amount sufficient to treat the periodontal diseases, wherein the solution has a pH of 7.4 to 7.6 and is stable for at least two months, and wherein the solution comprises anode water and cathode water, wherein the solution has a total amount of free chlorine species from 50 ppm to 80 ppm, wherein the free chlorine species comprises from 15 ppm to 35 ppm hypochlorous acid and from 25 ppm to 50 ppm sodium hypochlorite, wherein the solution causes no more than 3% of cells contacted to expose Annexin-V on their cellular surfaces when contacted with the ORP water solution for up to about thirty minutes.

2. The method of claim 1 , wherein the solution is stable for at least one year.

3. The method of claim 1 , wherein the cathode water is present in an amount of from about 10% by volume to about 50% by volume of the solution.

4. The method of claim 3 , wherein the cathode water is present in an amount of from about 20% by volume to about 40% by volume of the solution.

5. The method of claim 3 , wherein the anode water is present in an amount of from about 50% by volume to about 90% by volume of the solution.

6. The method of claim 1 , wherein the solution is administered to the patient by rinsing the oral cavity with the solution.

7. The method of claim 6 , wherein the solution is administered to the patient for at least 30 seconds.

8. The method of claim 7 , wherein the solution is administered to the patient for at least 2 minutes.

9. The method of claim 6 , wherein the solution is administered to the patient at least once a day.

10. The method of claim 9 , wherein the solution is administered to the patient at least three times a day.

Assignments (6)
CHANGE OF NAME Recorded Jan 5, 2017
From: OCULUS INNOVATIVE SCIENCES, INC.
To: SONOMA PHARMACEUTICALS, INC.
Reel/Frame 041257/0375 →
RELEASE OF LIEN Recorded Feb 24, 2015
From: VENTURE LENDING & LEASING V, INC.
To: OCULUS INNOVATIVE SCIENCES, INC.
Reel/Frame 035090/0111 →
RELEASE OF LIEN Recorded Feb 24, 2015
From: VENTURE LENDING & LEASING VI, INC.
To: OCULUS INNOVATIVE SCIENCES, INC.
Reel/Frame 035090/0143 →
SECURITY INTEREST Recorded Jul 7, 2011
From: OCULUS INNOVATIVE SCIENCES, INC.
To: VENTURE LENDING & LEASING V, INC.
Reel/Frame 026619/0196 →
SECURITY AGREEMENT Recorded Jul 7, 2011
From: OCULUS INNOVATIVE SCIENCES, INC.
To: VENTURE LENDING & LEASING VI, INC.
Reel/Frame 026619/0235 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 19, 2006
From: ALIMI, HOJABR
To: OCULUS INNOVATIVE SCIENCES, INC.
Reel/Frame 017961/0133 →
Continuity (7)
Provisional Application 60760635 · Jan 20, 2006
Provisional Application 60760567 · Jan 20, 2006
Provisional Application 60760645 · Jan 20, 2006
Provisional Application 60760557 · Jan 20, 2006
Provisional Application 60730743 · Oct 27, 2005
Provisional Application 60676883 · May 2, 2005
Related Publication 20060253060A1 · Nov 9, 2006