IP Library Granted Patent US 7,879,615
Granted Patent B2
US 7,879,615 · App. 11/425,818 · Granted Feb 1, 2011

Hemostasis analyzer and method

Assignee: Coramed Technologies, LLC
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Quick Facts
Patent No.
US 7,879,615
App. No.
11/425,818
Granted
Feb 1, 2011
Kind
B2
Abstract

A method and device for blood hemostasis analysis is disclosed. A blood sample is displaced to reach a resonant state. The resonant frequency of the blood sample is determined before, during and after a hemostasis process. The changes in the resonant frequency of the blood sample are indicative of the hemostasis characteristics of the blood sample.

Claims (19)

1. An apparatus for measuring hemostasis comprising:

a container adapted to hold a blood sample such that a surface of the blood sample is substantially unconstrained in one direction;

a shaker adapted to displace the container in order to cause an excitation of the blood sample and corresponding resonant displacement of the surface along the one direction; and

a sensor adapted to determine the resonant displacement of the surface along the one direction, wherein the direction is vertical and the surface is a bottom surface of the blood sample.

2. A method for measuring hemostasis comprising:

providing a blood sample;

exciting the blood sample to a resonant state by displacing the blood sample to create displacement of a surface of the blood sample in a direction;

observing the amplitude and frequency of the displacement of the surface of the blood sample;

determining a resonant frequency of the blood sample to provide a plurality of resonant frequencies of the blood sample based upon the observed amplitude and frequency of the surface; and

deriving a hemostasis characteristic of the blood sample from the plurality of resonant frequencies of the blood sample.

3. A method according to claim 2 , further comprising displacing the blood sample at a frequency, and incrementally varying the frequency until a resonant frequency of the blood sample is determined.

4. A method according to claim 2 , wherein displacing the blood sample comprises displacing the blood sample a at displacement frequency, the method further comprising incrementally varying the displacement frequency to determine the plurality of resonant frequencies of the blood sample before, during and after hemostasis of the blood sample, wherein the plurality of the resonant frequencies are indicative of the hemostasis characteristics of the blood sample.

5. A method according to claim 2 , further comprising:

displacing the blood sample with a frequency function, the frequency function having frequency components, and the frequency components being selected from a range of frequencies; and

determining a plurality of resonant frequencies of the blood sample before, during and after hemostasis of the blood sample;

wherein the plurality of the resonant frequencies are indicative of the hemostasis characteristics of the blood sample.

6. A method according to claim 2 , wherein the blood sample is supported in a column, the surface comprising a bottom surface of the column and step of displacing the sample comprises displacing the sample along an axis of the column.

7. A method according to claim 2 , comprising placing the blood sample in a container by injecting the blood into the container through a self-sealing port on the container.

8. A method according to claim 2 , wherein the determining a resonant frequency of the blood sample comprises either continuously determining a change in resonant frequency with time or periodically determining the resonant frequency.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 11, 2021
From: CORAMED TECHNOLOGIES, LLC
To: HAEMONETICS CORPORATION
Reel/Frame 054870/0781 →
CHANGE OF NAME Recorded Nov 20, 2008
From: HAEMOSCOPE CORPORATION
To: CORA HEALTHCARE, INC.
Reel/Frame 021861/0319 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 20, 2008
From: CORA HEALTHCARE, INC.
To: CORAMED TECHNOLOGIES, LLC
Reel/Frame 021861/0323 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 22, 2006
From: KAUTZKY, HANS
To: HAEMOSCOPE CORPORATION
Reel/Frame 017829/0880 →
Continuity (2)
Provisional Application 60728505 · Oct 20, 2005
Related Publication 20070092405A1 · Apr 26, 2007