IP Library Granted Patent US 7,402,682
Granted Patent B2
US 7,402,682 · App. 11/427,508 · Granted Jul 22, 2008

3-heteroaryl-3,5-dihydro-4-oxo-4

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Quick Facts
Patent No.
US 7,402,682
App. No.
11/427,508
Granted
Jul 22, 2008
Kind
B2
Abstract

A subject-matter of the invention is the compounds of general formula (I) in which X represents a hydrogen or halogen atom; R 1 represents a hydrogen atom or a (C 1 -C 4 )alkyl group; R 2 and R 3 each represent, independently of one another, a hydrogen atom or a (C 1 -C 4 )alkyl group or else R 2 and R 3 form, with the nitrogen atom which carries them, a pyrrolidinyl, piperidinyl, morpholinyl or 4-alkylpiperazinyl group; and Het represents a heteroaromatic group of pyridinyl, 1-oxidopyridinyl, quinolinyl, isoquinolinyl, pyrimidinyl, pyrazinyl or pyridazinyl type, it being possible for the heteroaromatic group to carry one or more halogen atoms and/or one or more (C 1 -C 4 )alkyl or (C 1 -C 4 )alkoxy groups; in the form of bases, of addition salts with acids, of solvates or of hydrates, the pharmaceutical compositions comprising them, processes for their preparation and synthetic intermediates.

Claims (5)

1. A compound of formula (II):

wherein

X is fluoro

R 1 represents a hydrogen atom or a (C 1 -C 4 )alkyl group,

R′ and R″ each represent, independently of one another, a (C 1 -C 4 )alkyl group.

Assignments (3)
CHANGE OF NAME Recorded Jun 20, 2012
From: SANOFI-AVENTIS
To: SANOFI
Reel/Frame 028413/0927 →
CHANGE OF NAME Recorded Jun 19, 2008
From: SANOFI-SYNTHELABO
To: SANOFI-AVENTIS
Reel/Frame 021119/0265 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 17, 2008
From: BURNIER, PHILIPPE; FROISSANT, JACQUES; MARABOUT, BENOIT; MARGUET, FRANK; PUECH, FREDERIC
To: SANOFI-SYNTHELABO
Reel/Frame 021105/0954 →