Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation
The present invention provides compositions of saratin and methods of use thereof. One aspect of the invention is a method of prevention or mitigation of the development of adhesions, keloids and scars. The adhesions, keloids and scars can be due to surgery, such as plastic surgery or orthopedic surgery, or can be pre-existing scars. Another aspect of the invention is a method for treatment of flexor tendon injuries.
1. A method of treating surgically-induced inflammation or a surgically-induced adhesion arising from tendon reconstructive surgery comprising locally administering at the site of the tendon reconstructive surgery an effective amount of saratin.
2. The method of claim 1 , wherein saratin is administered along the entire length of the exposed tendon.
3. The method of claim 1 , wherein saratin is administered at the interface of the suture connecting severed tendon ends.