Granted Patent
B2
US 7,985,756 · App. 11/551,667 · Granted Jul 26, 2011
Modulation of neurogenesis by PDE inhibition
Assignee:
BrainCells Inc.
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Abstract
The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The disclosure includes compositions and methods based on use of a PDE agent, optionally in combination with one or more other neurogenic agents, to stimulate or activate the formation of new nerve cells.
Claims (2)
1. A composition comprising rolipram and buspirone in concentrations effective to produce a synergistic effect in neurogenesis.
2. The composition of claim 1 , wherein said composition is in a pharmaceutically acceptable formulation.
Assignments (2)
SECURITY AGREEMENT
Recorded Aug 9, 2011
From: BRAINCELLS, INC.
To: SILICON VALLEY BANK
Reel/Frame 026724/0361 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Mar 16, 2007
From: BARLOW, CARROLEE; CARTER, TODD A.; LORRAIN, KYM I.; PIRES, JAMMIESON C.; TREUNER, KAI
To: BRAINCELLS, INC.
Reel/Frame 019023/0387 →
Continuity (4)
Provisional Application
60729366
· Oct 21, 2005
Provisional Application
60784605
· Mar 21, 2006
Provisional Application
60807594
· Jul 17, 2006