IP Library Granted Patent US 11,039,999
Granted Patent B2
US 11,039,999 · App. 11/570,680 · Granted Jun 22, 2021

Compositions suitable for treating cutaneous signs of aging

Inventors: Annebeth Siø Jensen (Virum, DK); Annette Strarup Kristensen (Rudersdal, DK); Henrik Enghusen Poulsen (Humlebaek, DK); Jana Vicanova (Prague, CZ); Nico Smit (Amsterdam, NL)
Assignee: Ferrosan APS
A61K8/676A23L33/105A23L33/15A61K8/27A61K8/678A61K8/735A61K8/9789A61Q19/08A23V2002/00
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Quick Facts
Patent No.
US 11,039,999
App. No.
11/570,680
Granted
Jun 22, 2021
Kind
B2
Abstract

Compositions comprising vitamin E, vitamin C, and white tea extract for treating cutaneous signs of aging are disclosed. The compositions reduce signs of wrinkles and improve other skin conditions, such as increased skin elasticity and skin softness. Moreover, the prevention or treatment of unhealthy skin, such as aged skin or skin overexposed to sunlight, may advantageously be accomplished by the administration of the compositions of the present invention The compositions includes the combination of a number of different components, which interact to provide the desired improvements to the skin Further advantageous ingredients of the compositions may comprise, naturally occurring antioxidants extracted from e g grape seeds and tomato, an extract comprising glycosaminoglycans, a transition metal component in an amount effective to bind collagen and elastic fibers and thicken skin, and a catechin-based component present in an amount sufficient to inhibit the presence of anti-collagen enzyme in the skin.

Claims (17)

1. An orally administered tablet or capsule for the treatment of cutaneous signs of aging in a mammal comprising an effective amount of Vitamin E, vitamin C, white tea extract, and an extract comprising glycosaminoglycans.

2. The tablet or capsule of claim 1 further comprising: Naturally occurring antioxidants extracted from grape seed, tomato, soy and/or chamomile, and at least one transition metal component.

3. The tablet or capsule of claim 2 , wherein the extract comprising glycosaminoglycans is cartilage extract.

4. The tablet or capsule of claim 3 , wherein the cartilage extract comprises chondroitin sulphate, keratan sulphate, hyaluronic acid, or dermatan sulphate or mixtures thereof.

5. The tablet or capsule of claim 2 , wherein the transition metal component is zinc.

6. The tablet or capsule of claim 5 , wherein zinc is in form of zinc gluconate.

7. The tablet or capsule of claim 6 further comprising pharmaceutically acceptable excipients.

8. A composition in the form of a tablet or capsule comprising: 0.1 to 60 weight % of vitamin E, 0.2 to 90 weight % of vitamin CU, and 0.2 to 90 weight % of white tea extract based on the total weight of the composition.

9. The composition in the form of a tablet or capsule of claim 8 further comprising 5 to 95 weight % of naturally occurring antioxidants extracted from grape seed, tomato, and/or chamomile, based on the total weight of the composition.

10. The composition in the form of a tablet or capsule of claim 9 further comprising 5 to 95 weight % of soy extract based on the total weight of the composition.

11. The composition in the form of a tablet or capsule of claim 10 , wherein vitamin E constitutes 0.5 to 20 weight % of the total weight of the composition.

12. The composition in the form of a tablet or capsule of claim 11 , wherein vitamin C constitutes 1 to 30 weight % of the total weight of the composition.

13. The composition in the form of a tablet or capsule of claim 12 , wherein vitamin E constitutes 1 to 10 weight % of the total weight of the composition.

14. The composition in the form of a tablet or capsule of claim 13 , wherein vitamin C constitutes 1 to 15 weight % of the total weight of the composition.

15. A tablet or capsule comprising the pharmaceutical composition of claim 8 along with pharmaceutically acceptable excipients.

16. A tablet or capsule formulation comprising an effective amount of Vitamin C, Vitamin E, White tea extract, Soy extract, Cartilage extract, Grape seed extract, Tomato extract, Zinc gluconate, and Pharmaceutically acceptable excipients.

17. The tablet or capsule formulation of claim 16 further comprising chamomile extract.

Assignments (2)
CHANGE OF NAME Recorded Apr 3, 2020
From: FERROSAN A/S
To: FERROSAN APS
Reel/Frame 052312/0968 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 9, 2007
From: JENSEN, ANNEBETH; KRISTENSEN, ANNETTE; POULSEN, HENRIK; VICANOVA, JANA; SMIT, NICO
To: FERROSAN A/S
Reel/Frame 019269/0448 →
Priority Claims (2)
DK PA200400995 · Jun 25, 2004 · national
DK PA200401397 · Sep 14, 2004 · national
Continuity (3)
Provisional Application 60582855 · Jun 25, 2004
Provisional Application 60609784 · Sep 14, 2004
Related Publication 20110262553A1 · Oct 27, 2011