IP Library Granted Patent US 7,446,526
Granted Patent B2
US 7,446,526 · App. 11/614,798 · Granted Nov 4, 2008

RF field mapping for magnetic resonance imaging

Assignee: The Board of Trustees of the Leland Stanford Junior University
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Quick Facts
Patent No.
US 7,446,526
App. No.
11/614,798
Granted
Nov 4, 2008
Kind
B2
Abstract

For in vivo magnetic resonance imaging at high field (≧3 T) it is essential to consider the homogeneity of the active B 1 field (B 1 +), particularly if surface coils are used for RF transmission. A new method is presented for highly rapid B 1 + magnitude mapping. It combines the double angle method with a B 1 -insensitive magnetization-reset sequence such that the choice of repetition time (TR) is independent of T 1 and with a multi-slice segmented (spiral) acquisition to achieve volumetric coverage with adequate spatial resolution in a few seconds.

Claims (15)

1. A method of mapping a field of a RF Excitation pulse (B 1 +) in the presence of a static field (B 0 ) for magnetic resonance imaging (MRI), comprising the steps of:

a) acquiring MRI signals in response to RF excitation pulse sequences alternately applied at two flip-angles, and

b) for each RF excitation pulse sequence at one flip angle, applying a reset pulse sequence for returning excited nuclei spins to a pre-excitation state, wherein the reset pulse sequence includes a first B 1 -insensitive and non-spatially selective saturation pulse and a second spin dephaser pulse.

2. The method of claim 1 , further comprising the step of:

c) using a ratio of the MRI signals acquired with the two flip angles as a measure of field of the RF excitation pulse for mapping the field of the RF excitation pulse in the presence of a static field.

3. The method of claim 2 wherein steps a) and b) are performed for each image reconstruction MRI acquisition.

4. The method of claim 1 wherein the second pulse follows the first pulse.

5. The method of claim 1 wherein the two flip-angles for the RF excitation pulse sequences are α 1 and α 2 , wherein α 2 =2α 1 .

6. The method of claim 5 wherein step a) includes interleaved multislice MRI signal acquisitions.

7. The method of claim 6 wherein the interleaved signal acquisitions are k-space spiral readouts.

8. The method of claim 5 wherein in step a) the ratio of the acquired signals I 1 and I 2 for flip-angle α 1 and α 2 , respectively, at spatial position, r, are indicative of the B 1 + field at position r.

9. The method of claim 8 wherein step a) includes interleaved multislice MRI signal acquisitions.

10. The method of claim 9 wherein the interleaved signal acquisitions are k-space spiral readouts.

11. The method of claim 10 wherein steps a) and b) are performed for each image reconstruction MRI acquisition.

12. The method of claim 8 wherein steps a) and b) are performed for each image reconstruction MRI acquisition.

Assignments (3)
CONFIRMATORY LICENSE Recorded Sep 15, 2011
From: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 026910/0465 →
CONFIRMATORY LICENSE Recorded May 27, 2008
From: STANFORD UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 020999/0348 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 27, 2007
From: CUNNINGHAM, CHARLES H.; PAULY, JOHN M.
To: BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, THE
Reel/Frame 018939/0811 →
Continuity (1)
Related Publication 20080150528A1 · Jun 26, 2008