IP Library Patent Application 11649720
Patent Application
App. No. 11/649,720

Plant cell having animal-type sugar chain adding function

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Quick Facts
Patent No.
US None
App. No.
11/649,720
Abstract

A plant cell having an animal-type sugar chain adding function is provided. The plant cell has an introduced gene encoding an enzyme derived from an animal, and the enzyme can transfer a fucose residue to a reducing terminal acetylglucosamine residue of a sugar chain of a glycoprotein.

Claims (12)

1 . A plant cell having an animal-type sugar chain adding function, wherein the plant cell has an introduced gene encoding an enzyme derived from an animal, and the enzyme can transfer a fucose residue to a reducing terminal acetylglucosamine residue of a sugar chain of a glycoprotein.

2 . A plant cell according to claim 1 , wherein the enzyme derived from an animal is α1,6-fucosyl transferase.

3 . A plant regenerated from a plant cell according to claim 1 .

4 . A method for producing a plant cell having an animal-type sugar chain adding function, comprising the step of introducing into the plant cell a gene encoding an enzyme derived from an animal, wherein the enzyme can transfer a fucose residue to a reducing terminal acetylglucosamine residue of a sugar chain of a glycoprotein.

5 . A method for producing a glycoprotein having an animal-type sugar chain, comprising the steps of:

transforming a plant cell by introducing into the plant cell a gene encoding an enzyme derived from an animal and a gene encoding an exogenous glycoprotein, wherein the enzyme can transfer a fucose residue to a reducing terminal acetylglucosamine residue of a glycoprotein, and

cultivating the resultant transformed plant cell.

6 . A method for producing a glycoprotein having an animal-type sugar chain, comprising the steps of:

transforming a plant cell by introducing into the plant cell a gene encoding an enzyme capable of transferring a fucose residue to a reducing terminal acetylglucosamine residue and a gene encoding an exogenous glycoprotein, and

expressing the enzyme in a cell organelle.

7 . A glycoprotein having an animal-type sugar chain produced by a method according to claim 6 .

8 . A plant regenerated from a plant cell according to claim 2.

Assignments (5)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 14, 2010
From: FUJIYAMA, KAZUHITO; SEKI, TATSUJI; TANIGUCHI, NAOYUKI
To: THE DOW CHEMICAL COMPANY
Reel/Frame 023782/0250 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 14, 2010
From: THE DOW CHEMICAL COMPANY
To: DFB BIOTECH, INC.
Reel/Frame 023783/0214 →
CHANGE OF NAME Recorded Jan 14, 2010
From: DFB BIOTECH, INC.
To: PHYTON, INC.
Reel/Frame 023783/0744 →
CHANGE OF NAME Recorded Jan 14, 2010
From: PHYTON, INC.
To: PHYTON HOLDINGS, LLC
Reel/Frame 023784/0901 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 25, 2008
From: FUJIYAMA, KAZUHITO; SEKI, TATSUJI; TANIGUCHI, NAOYUKI
To: DFB BIOTECH INC.
Reel/Frame 020413/0857 →