Use of xenon for treating neurointoxications
Methods for treating mammals for neurointoxication are provided comprising treating the mammal with a xenon-containing gas. Methods of providing neuroprotection in mammals are also disclosed comprising administering therapeutically effective amounts of xenon, preferably in combination with pharmaceutically acceptable carriers, diluents or excipients.
1. A method of reducing neurotoxicity caused by increased release of neurotransmitters during ischemia comprising:
administering to a mammal suffering from ischemia a therapeutically effective amount of xenon to reduce said neurotoxicity,
wherein the xenon is administered as a 90:10 percent by volume xenon-oxygen mixture.
2. A method of reducing neurotoxicity caused by increased release of neurotransmitters during ischemia comprising:
administering to a mammal suffering from ischemia a therapeutically effective amount of xenon to reduce said neurotoxicity,
wherein the xenon is administered with ambient air.
3. A method of reducing neuron death caused by increased release of neurotransmitters during ischemia comprising:
administering to a mammal suffering from ischemia a therapeutically effective amount of xenon to reduce the neuron death,
wherein the xenon is administered with ambient air.
4. A method of treating a mammal suffering from ischemia by reducing neurotoxicity caused by increased release of neurotransmitters during the ischemia, the method comprising:
administering to the mammal suffering from ischemia a therapeutically effective amount of xenon to reduce the neurotoxicity to treat the ischemia,
wherein the xenon is administered with ambient air.
5. A method of treating a mammal suffering from ischemia by reducing neuron death caused by increased release of neurotransmitters during the ischemia comprising:
administering to the mammal suffering from ischemia a therapeutically effective amount of xenon to reduce the neuron death to treat the ischemia,
wherein the xenon is administered with ambient air.
6. A method of treating a mammal suffering from acute ischemia comprising:
administering to the mammal suffering from acute ischemia a therapeutically effective amount of xenon to treat the acute ischemia,
wherein the xenon is administered as a 90:10 percent by volume xenon-oxygen mixture.
7. A method of treating a mammal suffering from acute ischemia comprising:
administering to the mammal suffering from acute ischemia a therapeutically effective amount of xenon to treat the acute ischemia,
wherein the xenon is administered with ambient air.
8. A method of reducing neuron death caused by increased release of neurotransmitters during ischemia comprising:
administering to a mammal suffering from ischemia a therapeutically effective amount of xenon to reduce the neuron death,
wherein the xenon is administered over several hours to one day.
9. A method of treating a mammal suffering from ischemia by reducing neurotoxicity caused by increased release of neurotransmitters during the ischemia, the method comprising:
administering to the mammal suffering from ischemia a therapeutically effective amount of xenon to reduce the neurotoxicity to treat the ischemia,
wherein the xenon is administered over several hours to one day.
10. A method of treating a mammal suffering from ischemia by reducing neuron death caused by increased release of neurotransmitters during the ischemia comprising:
administering to the mammal suffering from ischemia a therapeutically effective amount of xenon to reduce the neuron death to treat the ischemia,
wherein the xenon is administered over several hours to one day.
11. A method of treating a mammal suffering from acute ischemia comprising:
administering to the mammal suffering from acute ischemia a therapeutically effective amount of xenon to treat the acute ischemia,
wherein the xenon is administered over several hours to one day.