Mucosal or cutaneous medicinal or hygiene system
A mucosal or cutaneous medicinal or hygiene system, comprising (a) a gas-driven foam dispenser; and (b) a fluid composition comprising (i) as the only foaming agent one or more polysaccharides, gelatins, synthetic polymers selected from the group consisting of ethylene oxide homo- and copolymers having a weight average molecular weight of at least 10,000, and homo and copolymers comprising in polymerized form acrylic acid, an acrylic acid salt, acrylamide, vinylalcohol, vinylacetate, vinylpyrrolidone or vinylpyridine, or a combination thereof; (ii) a liquid diluent, and (iii) an active ingredient for mucosal or cutaneous medicinal treatment or hygiene.
1. A kit for delivering pharmaceutical compositions to be ingested, wherein the kit comprises
(a) a gas-driven foam dispenser and
(b) a separately packed volume of a propellant-less fluid composition containing no monomeric surfactants or polymeric surfactants with a weight average molecular weight of less than 8,000 and comprising
(i) as the only foaming agent one or more polysaccharides, having a weight average molecular weight of at least 10,000;
(ii) a liquid diluent, and
(iii) an active ingredient for oral medicinal treatment or hygiene,
wherein the viscosity of the fluid composition is from 2 to 50 mPa·s at 20° C.
2. The kit of claim 1 wherein the polysaccharide is a cellulose ether.
3. The kit of claim 1 wherein the cellulose ether is a C 1 -C 3 -alkyl cellulose, C 1 -C 3 -alkyl hydroxy-C 1-3 -alkyl cellulose, hydroxy-C 1-3 -alkyl cellulose or a mixed hydroxy-C 1 -C 3 -alkyl cellulose having a weight average molecular weight of from 12,000 to 100,000.
4. The kit of claim 1 comprising an air-driven foam dispenser (a) and a propellant-less fluid composition (b).
5. The kit of claim 1 wherein the polysaccharide is a hydroxypropyl methylcellulose or a methylcellulose.
6. The kit of claim 1 wherein the polysaccharide is a hydroxypropyl methylcellulose or methylcellulose having a weight average molecular weight of from 12,000 to 100,000.
7. The kit of claim 1 wherein the propellant-less fluid composition (b) comprises from 0.1 to 5 percent of one or more polysaccharides as the only foaming agent, based on the total weight of the fluid composition.
8. The kit of claim 1 wherein the propellant-less fluid composition (b) comprises from 0.005 to 5 percent of an active ingredient, based on the total weight of the fluid composition.