RNA interference pathway genes as tools for targeted genetic interference
Genes involved in double-stranded RNA interference (RNAi pathway genes) are identified and used to investigate the RNAi pathway. The genes and their products are also useful for modulating RNAi pathway activity.
1. An isolated antibody that specifically binds to the RDE-1 polypeptide as set forth in SEQ ID NO: 3.
2. The antibody of claim 1 , wherein the antibody is a single chain antibody.
3. The antibody of claim 1 , wherein the antibody is an antibody Fab fragment.
4. The antibody of claim 1 , wherein the antibody is a F(ab′) 2 fragment.
5. The antibody of claim 1 , wherein the antibody is a chimeric antibody.
6. The antibody of claim 1 , wherein the antibody is a polyclonal antibody.
7. The antibody of claim 1 , wherein the antibody is a monoclonal antibody.