Granted Patent
B2
US 7,498,411 · App. 11/726,699 · Granted Mar 3, 2009
P49/STRAP is a novel protein involved in gene regulation and cell proliferation
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Abstract
The invention provides isolated p49/STRAP protein, and isolated nucleic acids encoding a p49/STRAP protein. The inventors have discovered a new protein, named p49/STRAP that is expressed in cardiac tissue and other tissues in mammals. The p49/STRAP protein binds to serum response factor (SRF) and regulates transcription of SRF-responsive genes in the heart. p49/STRAP is also discovered to inhibit tumor cell proliferation, and thus the invention provides a method of inhibiting cancer cell proliferation by contacting the cells with p49/STRAP.
Claims (2)
1. An isolated peptide or protein comprising SEQ ID NO:1.
2. An isolated p49/STRAP protein that is a human p49/STRAP protein.
Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Nov 20, 2019
From: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
To: BIOVENTURES, LLC
Reel/Frame 051071/0811 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jan 30, 2009
From: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
To: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS; THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
Reel/Frame 022180/0199 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Mar 7, 2008
From: WEI, JEANNE Y.; ZHANG, XIAOMIN
To: BOARD OF TRUSTEES OF THE UNIVRSITY OF ARKANSAS, THE
Reel/Frame 020620/0883 →
Continuity (3)
Provisional Application
6061007000
· Sep 15, 2004