Non-destructive tissue repair and regeneration
A surgical stent made of biocompatible material for implantation in human tissue to enable blood and nutrients to flow from an area of vascular tissue to an area of tissue with little or no vasculature.
1. A method for facilitating healing of a tissue defect residing in an area of tissue, comprising:
providing a stent including an elongate body having a first end, a second end, and a length, the elongate body configured to allow passage of fluid therethrough;
inserting the stent into the area of tissue; and
positioning the stent so that a vascular area of tissue is accessible by the stent and the second end of the stent terminates adjacent to the tissue defect, whereby biological material from the vascular area of tissue is capable of traveling through the stent to the tissue defect to facilitate healing the tissue defect.
2. The method of claim 1 , wherein the step of inserting the stent into the area of tissue includes separating the tissue to provide an access for the stent without removing or ablating tissue.
3. The method of claim 1 , wherein the tissue defect resides in an avascular or partially vascular area of tissue.
4. The method of claim 1 , wherein the tissue defect is a tissue defect in a meniscus;
wherein the step of inserting the stent into the area of tissue includes inserting the stent into the meniscus.
5. The method of claim 1 , wherein the tissue defect is a tissue defect in an area of cartilage of a bone;
wherein the step of inserting the stent into the area of tissue includes inserting the stent into the bone; and
wherein the step of positioning the stent so that a vascular area of tissue is accessible by the stent and the second end of the stent terminates adjacent to the tissue defect includes positioning the stent so that biological material of the bone is accessible by the stent and the second end of the stent terminates adjacent to the tissue defect.
6. The method of claim 1 , further comprising:
delivering a biological treatment to the tissue defect via the stent.
7. The method of claim 6 , wherein the step of delivering a biological treatment to the tissue defect via the stent includes:
placing the biological treatment in fluid communication with the stent, whereby the biological treatment is capable of traveling through the stent to the tissue defect.
8. The method of claim 6 , wherein the step of delivering a biological treatment to the tissue defect via the stent includes:
coating the stent with the biological treatment.
9. The method of claim 6 , wherein the biological treatment includes platelet rich plasma.
10. The method of claim 6 , wherein the biological treatment includes bone marrow.
11. The method of claim 6 , wherein the biological treatment includes stem cells.
12. The method of claim 6 , wherein the biological treatment includes blood.
13. The method of claim 6 , wherein the biological treatment includes growth factors.
14. The method of claim 1 , wherein the positioning step includes trimming the stent to define the second end of the stent, whereby the second end defined by the trimming step terminates adjacent to the tissue defect.
15. The method of claim 1 , wherein the stent further includes a hollow tube which is open at both the first and the second ends of the stent to define end apertures, the positioning step including positioning the end aperture residing at the second end of the stent adjacent to the tissue defect.
16. The method of claim 15 , wherein the hollow tube includes a wall having a plurality of apertures sized to enable blood, nutrients and cells to enter the stent from the vascular area of tissue.
17. The method of claim 1 , wherein the stent is a porous rod.
18. The method of claim 1 , wherein an outer surface of the stent is smooth.
19. The method of claim 1 , wherein an outer surface of the stent is roughened.
20. The method of claim 1 , wherein an outer surface of the stent includes a rib.
21. The method of claim 1 , wherein an outer surface of the stent includes a plurality of ribs that encircle the outer surface.
22. The method of claim 20 , wherein the rib includes a thread, and wherein the positioning step includes threading the stent into the area of tissue.
23. The method of claim 22 , wherein the thread has a consistent pitch.
24. The method of claim 1 , wherein an outer surface of the stent includes a plurality of ribs that are substantially longitudinal and substantially parallel to a longitudinal axis of the stent.
25. The method of claim 1 , wherein the stent includes a collar for limiting the travel of the stent into tissue.
26. The method of claim 1 , wherein the positioning step positions the second end of the stent a distance of not more than one-quarter of the length of the stent from the tissue defect.
27. The method of claim 1 , wherein the positioning step positions the second end of the stent a distance of not more than three millimeters from the tissue defect.
28. The method of claim 1 , wherein the positioning step positions the stent so that the vascular area of tissue is accessible by the first end of the stent.
29. The method of claim 1 , wherein the biological material is selected from the group consisting of blood, blood components, cells, tissue, growth factors, bone marrow, bone marrow components, and stem cells.
30. The method of claim 4 , wherein the step of inserting the stent into the meniscus includes inserting the stent into the meniscus through the tissue defect.
31. A method for facilitating healing of a tissue defect residing in an area of tissue, comprising:
providing a stent including an elongate body having a first end and a second end, the elongate body configured to allow passage of fluid therethrough;
separating the tissue to allow insertion of the stent into the separated tissue without removing or ablating tissue;
inserting the stent into the separated tissue; and
positioning the stent so that a vascular area of tissue is accessible by the stent.
32. The method of claim 31 , wherein the positioning step further includes:
positioning the stent so that the second end of the stent terminates adjacent to the tissue defect, whereby biological material from the vascular area of tissue is capable of traveling through the stent to the tissue defect to facilitate healing the tissue defect.
33. The method of claim 31 , wherein the tissue defect resides in an avascular or partially vascular area of tissue.
34. The method of claim 31 , wherein the tissue defect is a tissue defect in a meniscus;
wherein the step of inserting the stent into the separated tissue includes inserting the stent into the meniscus.
35. The method of claim 31 , wherein the tissue defect is a tissue defect in an area of cartilage of a bone;
wherein the step of inserting the stent into the separated tissue includes inserting the stent into the bone;
wherein the step of positioning the stent so that a vascular area of tissue is accessible by the stent includes positioning the stent so that biological material of the bone is accessible by the stent and the second end of the stent terminates adjacent to the tissue defect.
36. The method of claim 31 , further comprising:
delivering a biological treatment to the tissue defect through the stent.
37. The method of claim 36 , wherein the step of delivering a biological treatment to the tissue defect through the stent includes:
placing the biological treatment in fluid communication with the stent, whereby the biological treatment is capable of traveling through the stent to the tissue defect.
38. The method of claim 36 , wherein the step of delivering a biological treatment to the tissue defect through the stent includes:
coating the stent with the biological treatment.
39. The method of claim 36 , wherein the biological treatment includes platelet rich plasma.
40. The method of claim 36 , wherein the biological treatment includes bone marrow.
41. The method of claim 36 , wherein the biological treatment includes stem cells.
42. The method of claim 36 , wherein the biological treatment includes blood.
43. The method of claim 36 , wherein the biological treatment includes growth factors.
44. The method of claim 31 , wherein the positioning step includes trimming the stent to define the second end of the stent, whereby the second end defined by the trimming step terminates adjacent to the tissue defect.
45. The method of claim 31 , wherein the stent further includes a hollow tube which is open at both the first and the second ends of the stent to define end apertures, the positioning step including positioning the end aperture residing at the second end of the stent adjacent to the tissue defect.
46. The method of claim 45 , wherein the hollow tube includes a wall having a plurality of apertures sized to enable blood, nutrients and cells to enter the stent from the vascular area of tissue.
47. The method of claim 31 , wherein the stent is a porous rod.
48. The method of claim 31 , wherein an outer surface of the stent is smooth.
49. The method of claim 31 , wherein an outer surface of the stent is roughened.
50. The method of claim 31 , wherein an outer surface of the stent includes a rib.
51. The method of claim 31 , wherein an outer surface of the stent includes a plurality of ribs that encircle the outer surface.
52. The method of claim 50 , wherein the rib includes a thread, and wherein the positioning step includes threading the stent into the area of tissue.
53. The method of claim 52 , wherein the thread has a consistent pitch.
54. The method of claim 31 , wherein an, outer surface of the stent includes a plurality of ribs that are substantially longitudinal and substantially parallel to a longitudinal axis of the stent.
55. The method of claim 31 , wherein the stent includes a collar for limiting the travel of the stent into tissue.
56. The method of claim 31 , wherein the positioning step positions the second end of the stent a distance of not more than one-quarter of the length of the stent from the tissue defect.
57. The method of claim 31 , wherein the positioning step positions the second end of the stent a distance of not more than three millimeters from the tissue defect.
58. The method of claim 31 , wherein the positioning step positions the stent so that the vascular area of tissue is accessible by the first end of the stent.
59. The method of claim 34 , wherein the step of inserting the stent into the meniscus includes inserting the stent into the meniscus through the tissue defect.