Patent Application
App. No. 11/750,542
USE OF ANTIMICROBIAL PROTEINS AND PEPTIDES FOR THE TREATMENT OF OTITIS MEDIA AND PARANASAL SINUSITIS
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Abstract
The pharmaceutical composition and a method of treatment of infectious diseases, such as otitis media, paranasal sinusitis, labyrinthitis and meningitis are described. The composition comprises EP2E or homologues thereof.
Claims (3)
1 . A pharmaceutical composition comprising a pharmacologically effective amount of EP2E polypeptide, wherein said amount of EP2E polypeptide is sufficient to treat a microbial infection in a mammal.
2 . The composition of claim 1 , wherein said infection is selected from the group consisting of otitis media, paranasal sinusitis, labyrinthitis and meningitis.
3 . The composition of claim 1 , wherein said EP2E polypeptide is synthesized chemically and refolded by oxidative refolding.