Polymer-coated magnetic particles comprising a 2,3-hydroxypropyl group, and probe-bonded particles
A method for producing magnetic particles includes forming a hydrophobic first polymer layer on the surface of a mother particle containing superparamagnetic particles, forming a second polymer layer having glycidyl groups at least on its surface on the first polymer layer, and introducing a polar group containing one or more of at least one atom selected from the group consisting of an oxygen atom, a nitrogen atom, and a sulfur atom by chemically modifying the glycidyl groups.
1. A magnetic particle comprising:
a mother particle containing superparamagnetic particles;
a hydrophobic first polymer layer formed on the surface of the mother particle; and
a second polymer layer having an amino group and a 2,3-hydroxypropyl group formed on the first polymer layer.
2. The magnetic particle according to claim 1 ,
wherein the mother particle comprises a nuclear particle and a magnetic material layer containing the superparamagnetic particles formed on the surface of the nuclear particle; and
wherein the first polymer layer is formed on the magnetic material layer.
3. The magnetic particle according to claim 1 , which is used for probe bonding.
4. A probe-bonded particle comprising the magnetic particle according to claim 1 , and a probe bonded to the magnetic particle.
5. A magnetic particle comprising:
a mother particle containing superparamagnetic particles;
a hydrophobic first polymer layer formed on the surface of the mother particle; and
a second polymer layer having an aldehyde group and a 2,3-hydroxypropyl group formed on the first polymer layer.
6. The magnetic particle according to claim 5 ,
wherein the mother particle comprises a nuclear particle and a magnetic material layer containing the superparamagnetic particles formed on the surface of the nuclear particle; and
wherein the first polymer layer is formed on the magnetic material layer.
7. The magnetic particle according to claim 5 , which is used for probe bonding.
8. A probe-bonded particle comprising the magnetic particle according to claim 5 , and a probe bonded to the magnetic particle.
9. A magnetic particle comprising:
a mother particle containing superparamagnetic particles;
a hydrophobic first polymer layer formed on the surface of the mother particle; and
a second polymer layer having a carboxyl group and a 2,3-hydroxypropyl group formed on the first polymer layer.
10. The magnetic particle according to claim 9 ,
wherein the mother particle comprises a nuclear particle and a magnetic material layer containing the superparamagnetic particles formed on the surface of the nuclear particle; and
wherein the first polymer layer is formed on the magnetic material layer.
11. The magnetic particle according to claim 9 , which is used for probe bonding.
12. A probe-bonded particle comprising the magnetic particle according to claim 9 , and a probe bonded to the magnetic particle.
13. A magnetic particle comprising:
a mother particle containing superparamagnetic particles;
a hydrophobic first polymer layer formed on the surface of the mother particle; and
a second polymer layer having an active ester group and a 2,3-hydroxypropyl group formed on the first polymer layer.
14. The magnetic particle according to claim 13 ,
wherein the mother particle comprises a nuclear particle and a magnetic material layer containing the superparamagnetic particles formed on the surface of the nuclear particle; and
wherein the first polymer layer is formed on the magnetic material layer.
15. The magnetic particle according to claim 13 , which is used for probe bonding.
16. A probe-bonded particle comprising the magnetic particle according to claim 13 , and a probe bonded to the magnetic particle.