Patent Application
App. No. 11/825,293
Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity
Loading inventors, assignments & file history…
Abstract
The present invention provides peptide analogues which are antagonists of gastric inhibitory peptide (GIP). The peptides, based on GIP 1-42 include substitutions and/or modifications which have enhanced resistance to degradation by the enzyme dipeptidyl peptidase IV (DPP IV). The invention also provides a process of N terminally modifying GIP and the use of the peptide analogues for treatment of diabetes.
Claims (2)
1 . A peptide analogue of GIP(1-42) (SEQ ID NO:1), comprising at least 12 amino acid residues from the N-terminal end of GIP(3-42).
2 - 38 . (canceled)
Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 6, 2009
From: GAULT, VICTOR A; O'HARTE, FINBARR PAUL MARY; IRWIN, NIGEL; HARRIOTT, PATRICK; FLATT, PETER RAYMOND
To: UUTECH LIMITED
Reel/Frame 022218/0019 →