Granted Patent
B2
US 7,776,593 · App. 11/835,391 · Granted Aug 17, 2010
Hes6 as a marker of pancreatic endocrine cells
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Abstract
The present invention provides methods of identifying endocrine stem and progenitor cells.
Claims (5)
1. A method for identifying endocrine stem cells, comprising the steps of
(a) contacting at least one test cell with a detectable agent specific for Hes6;
(b) detecting the presence of Hes6 (Hairy/Enhancer of Split 6);
(c) identifying said test cell as an endocrine stem cell if the presence of Hes6 is detected.
2. The method of claim 1 , wherein said detectable agent comprises an anti-Hes6 antibody or a nucleic acid complementary to mRNA encoding Hes6.
Assignments (4)
CONFIRMATORY LICENSE
Recorded Oct 12, 2010
From: UNIVERSITY OF CALIFORNIA SAN DIEGO
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 025114/0570 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Sep 30, 2009
From: LEVINE, FRED
To: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Reel/Frame 023308/0591 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Sep 30, 2009
From: TYRBERG, BJOERN
To: BURNHAM INSTITUTE FOR MEDICAL RESEARCH
Reel/Frame 023308/0945 →
CONFIRMATORY LICENSE
Recorded May 28, 2008
From: UNIVERSITY OF CALIFORNIA SAN DIEGO
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 021007/0238 →
Continuity (2)
Provisional Application
6082169800
· Aug 7, 2006