Dermatological composition
Dermatological compositions containing a humectant, e.g., at least one of urea, ammonium lactate, and glycerin, and an emollient, e.g., at least one of Shea or cocoa butter, glycine soja sterol and hybrid sunflower oil. The compositions of the invention may be utilized for treatment or amelioration of skin disorders or adverse physiological conditions, and such compositions may be employed as a base for cosmetic or pharmaceutical formulations for dermal administration.
1. A dermatological composition, consisting of water and the following components in the following respective concentration ranges:
Concentration Range,
Component
Weight %
Urea
1%-50%
Butylated Hydroxytoluene
0.05%-0.5%
Butyrospermum Parkii (Shea
0.5%-10%
Butter) Fruit
Disodium EDTA
0.05%-0.3%
Glyceryl Stearate
2.0%-10.0%
Glycine Soja (Soybean) Sterol
1.0%-4.0%
Helianthus Annuus (Hybrid
2.0%-15%
Sunflower) Oil
Sodium Polyacrylate
0.1%-1.5%
Stearic Acid
3.0%-8.0%
Triethanolamine
0.25%-2.5%
wherein weight % is based on the total weight of the composition and the weight percentages of all components in the composition totals 100%.
2. A dermatological composition according to claim 1 , wherein the concentration of urea is in a range of from 21 to 40 weight %.
3. A dermatological composition according to claim 1 , wherein the composition consists of water and the following components in the following respective concentrations:
Component
Weight %
Urea
40.0%
Butylated Hydroxytoluene
0.2%
Butyrospermum Parkii (Shea
2.0%
Butter) Fruit
Disodium EDTA
0.1%
Glyceryl Stearate
3.0%
Glycine Soja (Soybean) Sterol
2.0%
Helianthus Annuus (Hybrid
8.0%
Sunflower) Oil
Sodium Polyacrylate
0.6%
Stearic Acid
4.0%
Triethanolamine
1.0%
4. The composition of claim 3 , in the form of a suspension.
5. A dermatological composition according to claim 1 , wherein the composition consists of water and the following components in the following respective concentrations:
Component
Weight %
Urea
40.0%
Butylated Hydroxytoluene
0.2%
Butyrospermum Parkii (Shea
2.0%
Butter) Fruit
Disodium EDTA
0.1%
Glyceryl Stearate
3.0%
Glycine Soja (Soybean) Sterol
2.0%
Helianthus Annuus (Hybrid
10.0%
Sunflower) Oil
Sodium Polyacrylate
1.0%
Stearic Acid
4.0%
Triethanolamine
1.0%
6. The composition of claim 5 , in the form of an emulsion.
7. A dermatological composition consisting of water and the following components in the following respective concentration ranges:
Concentration Range,
Component
Weight %
Urea, glycerin
1%-50%
Butylated Hydroxytoluene
0.05%-0.5%
Butyrospermum Parkii (Shea
0.5%-10%
Butter) Fruit, wax
Disodium EDTA
0.05%-0.3%
Helianthus Annuus (Hybrid
2.0%-15%
Sunflower) Oil
Sodium Polyacrylate,
0.1%-1.5%
polyacrylamides, wax, paraffins
Lauric Acid
3.0%-8.0%
and further comprising water, wherein weight % is based on the total weight of the composition and the weight percentages of all components in the composition totals 100%.
8. The dermatological composition of claim 7 , wherein the concentration of urea is 40%.
9. A method for treating a skin condition selected from the group consisting of psoriasis, xerosis, ichthyosis, keratosis, keratoderma, dermatitis, pruritus, eczema and calluses comprising topically applying an effective amount of the composition of claim 1 to a subject having said skin condition.
10. A method for softening skin tissue or softening nails comprising topically applying an effective amount of the composition of claim 1 to skin or nails of a subject in need thereof.
11. A lotion, cream, ointment, emulsion, suspension or gel consisting essentially of the dermatological composition of any one of claims 1 , 3 , 5 , or 7 .