Bag proteins and nucleic acid molecules encoding them
The present invention provides a family of BAG-1 related proteins from humans (BAG-1L, BAG-1, BAG-2, BAG-3, BAG-4 and BAG-5), the invertebrate C. elegans (BAG-1, BAG-2) and the fission yeast S. pombe (BAG-1A, BAG-1B) and the nucleic acid molecules that encode them.
1. A substantially purified nucleic acid molecule encoding the amino acid sequence of SEQ ID NO:8.
2. The nucleic acid molecule of claim 1 , wherein said nucleic acid molecule has the nucleotide sequence SEQ ID NO:7.
3. A substantially purified nucleic acid molecule consisting of a fragment of at least 35 nucleotides of a nucleotide sequence, or the complement thereof, encoding a polypeptide comprising the amino acid sequence of SEQ ID NO:8.
4. The nucleic acid molecule of claim 3 , wherein said fragment is at least 45 nucleotides.
5. The nucleic acid molecule of claim 3 , wherein said fragment is at least 55 nucleotides.
6. A substantially purified nucleic acid molecule consisting of a fragment of at least 35 nucleotides of the nucleotide sequence of SEQ ID NO:7, or the complement thereof.
7. The nucleic acid molecule of claim 6 , wherein said fragment is at least 45 nucleotides.
8. The nucleic acid molecule of claim 6 , wherein said fragment is at least 55 nucleotides.