IP Library Patent Application 11891048
Patent Application
App. No. 11/891,048

Levalbuterol salt

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Quick Facts
Patent No.
US None
App. No.
11/891,048
Abstract

Levalbuterol L-tartrate affords crystals possessing properties desirable for use in a metered dose inhaler.

Claims (17)

1 - 29 . (canceled)

30 . Levalbuterol L-tartrate, which is a hemitartrate.

31 . A pharmaceutical composition comprising the levalbuterol L-tartrate of claim 30 .

32 . The pharmaceutical composition of claim 31 , which further comprises a propellant.

33 . The pharmaceutical composition of claim 32 , wherein the propellant is 1,1,1,2-tetrafluoroethane.

34 . The pharmaceutical composition of claim 31 , which further comprises a surfactant.

35 . The pharmaceutical composition of claim 34 , wherein the surfactant is oleic acid.

36 . The pharmaceutical composition of claim 31 , which further comprises a co-solvent.

37 . The pharmaceutical composition of claim 36 , wherein the co-solvent is ethanol.

38 . The pharmaceutical composition of claim 37 , wherein the ethanol is dehydrated ethanol.

39 . The pharmaceutical composition of claim 31 , which is adapted for administration by inhalation using a metered dose inhaler.

40 . The pharmaceutical composition of claim 39 , which is adapted for administration of from about 45 μg to about 90 μg levalbuterol free base per actuation.

41 . A pharmaceutical composition comprising levalbuterol L-tartrate, 1,1,1,2-tetrafluoroethane, oleic acid, and ethanol.

42 . The pharmaceutical composition of claim 41 , wherein the ethanol is dehydrated ethanol.

43 . The pharmaceutical composition of claim 42 , which is adapted for administration by inhalation using a metered dose inhaler.

44 . The pharmaceutical composition of claim 43 , wherein one gram of the composition contains about 1.04 mg of levalbuterol L-tartrate, about 0.951 g of 1,1,1,2-tetrafluoroethane, about 0.0521 mg of oleic acid, and about 0.0476 g of dehydrated ethanol.

45 . The pharmaceutical composition of claim 43 , wherein one gram of the composition contains about 2.08 mg of levalbuterol L-tartrate, about 0.95 g of 1,1,1,2-tetrafluoroethane, about 0.104 mg of oleic acid, and about 0.0475 g of dehydrated ethanol.

Assignments (1)
CHANGE OF NAME Recorded Dec 9, 2010
From: SEPRACOR INC.
To: SUNOVION PHARMACEUTICALS INC.
Reel/Frame 025484/0050 →