IP Library Granted Patent US 8,034,955
Granted Patent B2
US 8,034,955 · App. 11/927,418 · Granted Oct 11, 2011

Therapeutic compounds and methods of use

Assignee: Trustees of Dartmouth College
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Quick Facts
Patent No.
US 8,034,955
App. No.
11/927,418
Granted
Oct 11, 2011
Kind
B2
Abstract

Compounds and methods useful for chemopreventative treatment of diseases such as cancer, Alzheimer's disease, Parkinson's disease, inflammatory bowel diseases, and multiple sclerosis.

Claims (10)

1. A pharmaceutical composition, comprising a therapeutically effective amount of a compound having the formula:

and a pharmaceutically acceptable carrier.

2. The composition of claim 1 , wherein the composition is formulated for oral delivery.

3. The composition of claim 2 , wherein the composition is formulated as a hard or soft capsule, a tablet, a syrup, a suspension, a wafer, or an elixir.

4. The composition of claim 3 , wherein the soft capsule is a gelatin capsule.

5. The composition of claim 2 , further comprising a protective coating.

6. The composition of claim 1 , wherein the compound is dispersed in a liposome.

7. The composition of claim 1 , wherein the compound is dispersed in an oil and water emulsion or a water and oil emulsion.

8. A compound having the following structure:

9. A compound having the following structure:

Assignments (2)
CONFIRMATORY LICENSE Recorded Nov 29, 2011
From: DARTMOUTH COLLEGE
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 027290/0578 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 3, 2009
From: GRIBBLE, GORDON W.; HONDA, TADASHI; SPORN, MICHAEL B.; SUH, NANJOO
To: TRUSTEES OF DARTMOUTH COLLEGE
Reel/Frame 023462/0245 →
Continuity (5)
Continuation 10395372 · Mar 24, 2003
Continuation 09927081 · Aug 9, 2001
Division 09335003 · Jun 17, 1999
Provisional Application 60090053 · Jun 19, 1998
Related Publication 20080220057A1 · Sep 11, 2008