IP Library › Patent Application 11929951
Patent Application
App. No. 11/929,951

Pancreatic Cancer Genes

Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US None
App. No.
11/929,951
Abstract

The present invention provides the art with the DNA coding sequences of polynucleotides that are up-or-down-regulated in cancer and dysplasia. These polynucleotides and encoded proteins or polypeptides can be used in the diagnosis or identification of cancer and dysplasia. Inhibitors of the up-regulated polynucleotides and proteins can decrease the abnormality of cancer and dysplasia. Enhancing the expression of down-regulated polynucleotides or introducing down-regulated proteins to cells can decrease the growth and/or abnormal characteristics of cancer and dysplasia.

Claims (3)

1 . A method of diagnosing dysplasia in a patient comprising comparing the amount of a polypeptide in a patient sample and in a normal sample, wherein said polypeptide comprises the polypeptide encoded by SEQ ID NO:13, or a naturally occurring variant of SEQ ID NO:13, wherein said naturally occurring variant hybridizes to SEQ ID NO:13 under conditions including a wash in 2×SCC, 0.1% SDS at 50° C. for 20 minutes; and wherein a patient sample containing more of said polypeptide than the normal sample is identified as dysplastic.

2 . The method of claim 2 , wherein the dysplasia is pancreatic dysplasia.

3 . The method of claim 1 , wherein the patient sample and the normal sample comprise pancreatic cells.