Method for calibrating blood analysis machines

1. A method for calibrating machines to effect an analysis of a blood sample by measuring erythrocyte sedimentation rate (ESR) and/or aggregation of red corpuscles, wherein measurement is performed by exploiting optical density kinetics obtained from measurement of variation in optical density of said blood sample in an interval of time, comprising a measuring step in which, the same machine with which the measurement of the optical density is performed on said blood sample, wherein a first measurement is performed of the optical density of a first of at least two latexes, or turbidimetric samples, having a known optical density that is reproducible and measurable, and wherein a second measurement is performed of the optical density of a second of said at least two latexes having a known optical density that is reproducible, measurable and different from the optical density of said first latex, and a calibration step, in which the difference is calculated between the values of optical density of at least said first and second of said at least two latexes as obtained from the measurements performed by the machine and the known values of optical density, to determine at least one correction factor usable to calibrate said machine.

2. The method as in claim 1 , wherein said optical density kinetics is obtained from a sudden stoppage of flow of said blood sample through a measuring cell.

3. The method as in claim 1 , wherein said correction factor is a value proportional to gain to be assigned to the machine.

4. The method as in claim 1 , wherein said latexes are of natural or synthetic origin.

5. The method as in claim 1 wherein the optical densities of said latexes or of analogous or comparable substances, is substantially independent with respect to temperature and pressure.

6. The method as in claim 1 , wherein during said measuring step, said latexes are analyzed separately in a single calibration process, in order to obtain relative different values of optical density.

7. The method as in claim 1 , wherein during said measuring step, said latexes are analyzed in sequence in a single calibration process, in order to obtain relative different values of optical density.

8. The method as in claim 1 , wherein during said measuring step, the values measured are memorized electronically.

9. The method as in claim 1 , wherein said method is independent of environmental conditions where the machine is located.

10. The method as in claim 1 , wherein the values of optical density of said at least two latexes comprise a minimum and maximum range of variation in optical density caused by said blood sample which is made to flow through a measuring capillary and which flow is suddenly stopped, defining a characteristic curve of optical density of the blood sample.

11. The method as in claim 1 , wherein the optical density measured for the first of said two latexes represents the optical density of the beginning of the optical density kinetics, caused by a sudden stoppage of the flow of said blood sample, and the optical density measured for the second of said two latexes represents the optical density after a pre-fixed measuring time.

12. The method as in claim 1 , wherein during said measuring step, said optical density is measured by emitting from an emitter an electromagnetic wave or a sound wave and by detecting said electromagnetic wave or said sound wave by a detector.