IP Library › Patent Application 12011828
Patent Application
App. No. 12/011,828

Blood group antigen fusion polypeptides and methods of use thereof

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Quick Facts
Patent No.
US None
App. No.
12/011,828
Abstract

The present invention provides compositions and methods for treating or preventing antibody mediated graft rejection.

Claims (7)

1 . An absorber comprising a fusion polypeptide, wherein the fusion polypeptide comprises a first polypeptide operably linked to a second polypeptide, wherein the first polypeptide:

(a) is a mucin polypeptide and

(b) is glycosylated by an α1,2 fucosyltransferase and

the second polypeptide comprises at least a region of an immunoglobulin polypeptide.

2 . A method removing an antibody from a biological sample, the method comprising

(a) contacting a biological sample with the absorber of claim 1 to form an absorber-antibody complex; and

(b) removing the complex from the biological sample thereby removing the antibody from the biological sample.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 3, 2017
From: ABSORBER AB
To: OLERUP SSP AB
Reel/Frame 041166/0459 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 17, 2009
From: LOFLING, JONAS; HOLGERSSON, JAN
To: ABSORBER AB
Reel/Frame 022560/0639 →