Multivariable antigens complexed with targeting humanized monoclonal antibody

1. A modular recombinant rAb carrier comprising an antigen-specific binding domain linked to one or more antigen carrier domains wherein the antigen carrier domain comprising a dockerin domain or a cohesion domain capable of forming a cohesin-dockerin binding pair, and wherein the antigen-binding domain binds a dendritic cell immunoreceptor.

2. The rAb carrier of claim 1 , wherein the antigen-specific binding domain comprises an immunoglobulin heavy chain or light chain.

3. The rAb carrier of claim 2 , wherein the C-terminus of the heavy chain of said antigen-specific binding domain is fused to the dockerin domain or the cohesin domain to form a fusion protein.

4. The rAb carrier of claim 1 , further comprising a complementary dockerin or cohesin domain bound to an antigen that forms a complex with the modular rAb carrier.

5. The rAb carrier of claim 1 , further comprising a complementary dockerin or cohesin domain that is fused with an antigen.

6. The rAb carrier of claim 1 , wherein the antigen-specific domain comprises a full length antibody, an antibody variable region domain, an Fab fragment, a Fab′ fragment, an F(ab) 2 fragment, an Fv fragment, or an Fabc fragment.

7. The rAb carrier of claim 1 , wherein the cohesin-dockerin are from Bacteroides cellulosolvens.

8. The rAb carrier of claim 1 , wherein the rAb carrier is further defined as: an rAb.Doc.

9. The rAb carrier of claim 4 , wherein the rAb carrier is further defined as being part of a complex: an rAb.Doc:Coh.antigen.

10. A bivalent and multivalent (rAb 1 .Doc:Coh.rAb 2 ) self-assembled conjugate, wherein the antigen-specific binding domains rAb 1 and rAb 2 bind a cell surface marker wherein the cell surface marker is the dendritic cell immunoreceptor.