IP Library › Granted Patent US 11,612,553
Granted Patent B2
US 11,612,553 · App. 12/058,209 · Granted Mar 28, 2023

Oral care product and methods of use and manufacture thereof

Inventors: Michael Prencipe (West Windsor, NJ); Ravi Subramanyam (Belle Mead, NJ); Sarita V. Mello (Somerset, NJ); Donghui Wu (Bridgewater, NJ); Suman Chopra (Monroe, NJ); Andre M. Morgan (Robbinsville, NJ); Diane Cummins (Livingston, NJ); Richard J. Sullivan (Atlantic Highlands, NJ); Ralph Peter Santarpia, III (Edison, NJ); Lynette Zaidel (Cranford, NJ); Qin Wang (Monmouth Junction, NJ); Gary Edward Tambs (Belle Mead, NJ); Virginia Monsul Barnes (Ringoes, NJ); Rajnish Kohli (Hillsborough, NJ); Richard Scott Robinson (Belle Mead, NJ); Sergio Leite (Kendall Park, NJ); Eric A. Simon (Somerset, NJ)
Assignee: Colgate-Palmolive Company
A61K8/44A61K8/19A61K8/21A61K8/24A61K31/198A61Q11/00
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Quick Facts
Patent No.
US 11,612,553
App. No.
12/058,209
Granted
Mar 28, 2023
Kind
B2
Abstract

This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form, together with an antibacterial agent, and to methods of using and of making such compositions.

Claims (23)

1. An oral care composition comprising

a. arginine phosphate in an amount of from 1% to 10% by weight of the composition, the weight of arginine being calculated as free base form;

b. a zinc salt, comprising zinc citrate, in an amount of 0.01 to 5% by weight of the composition;

c. a surfactant mixture comprising sodium lauryl sulfate and cocoamidopropyl betaine, wherein the surfactant mixture in an amount of 0.1 to 5% by weight of the composition; and

d. an anionic polymer in an amount of 0.05 to 5% by weight of the composition;

wherein the composition has a pH of 6.8 to 7.2.

2. The composition of claim 1 further comprising an effective amount of a fluoride source.

3. A composition according to claim 1 further comprising one or more of arginine bicarbonate, and arginine hydrochloride.

4. A composition according to claim 1 wherein the composition comprises a humectant which consists of glycerin.

5. A composition according to claim 1 wherein the anionic polymer is a copolymer of methyl vinyl ether and maleic anhydride or is xanthan gum.

6. A composition according to claim 1 which is a dentifrice wherein the composition further comprises an effective amount of a soluble fluoride salt selected from sodium fluoride and sodium monofluophosphate; and

the anionic polymer is a copolymer of methyl vinyl ether and maleic anhydride.

7. A composition according to claim 1 further comprising xylitol.

8. A composition according to claim 1 further comprising a particulate material selected from silica and calcium carbonate.

9. A composition according to claim 1 having a radioactive dentin abrasion (RDA) less than about 150.

10. The composition according to claim 1 in the form of a toothpaste further comprising one or more of water, abrasives, surfactants, foaming agents, vitamins, polymers, enzymes, humectants, thickeners, antimicrobial agents, preservatives, flavorings, colorings and/or combinations thereof.

11. An oral care composition according to claim 1 further comprising a soluble fluoride salt in an amount of from 0.01 to 2 wt % of the total composition weight.

12. An oral care composition according to claim 1 further comprising a source of fluoride ions in an amount to provide 50 to 25,000 ppm by weight of fluoride ions in the total composition weight.

13. An oral care composition according to claim 11 wherein the soluble fluoride salt is selected from sodium fluoride, sodium monofluorophosphate, and mixtures thereof.

14. An oral care composition according to claim 1 further comprising an abrasive material, the abrasive material including a small particle fraction comprising at least about 5 wt % of the total composition weight, wherein the particles of the small particle fraction have a d50 of less than 5 μm.

15. An oral care composition according to claim 14 wherein the small particle fraction comprises at least about 20 wt % of the total composition weight.

16. An oral care composition according to claim 14 wherein the abrasive material is selected from calcium carbonate, silica, and mixtures thereof.

17. An oral care composition according to claim 14 wherein the abrasive material comprises from 15 to 70 wt % of the total composition weight.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 18, 2008
From: PRENCIPE, MICHAEL; SUBRAMANYAM, RAVI; MELLO, SARITA V.; WU, DONGHUI; CHOPRA, SUMAN; MORGAN, ANDRE M.; CUMMINS, DIANE; SULLIVAN, RICHARD J.; SANTARPIA, RALPH PETER, III; ZAIDEL, LYNETTE; WANG, QIN; TAMBS, GARY EDWARD; BARNES, VIRGINIA MONSUL; KOHLI, RAJNISH; ROBINSON, RICHARD SCOTT; LEITE, SERGIO; SIMON, ERIC A.
To: COLGATE-PALMOLIVE COMPANY
Reel/Frame 021114/0074 →
Continuity (4)
Provisional Application 61027432 · Feb 8, 2008
Provisional Application 61027420 · Feb 8, 2008
Provisional Application 61027431 · Feb 8, 2008
Related Publication 20090202454A1 · Aug 13, 2009