IP Library › Granted Patent US 7,589,119
Granted Patent B2
US 7,589,119 · App. 12/072,011 · Granted Sep 15, 2009

Methods for treating or preventing metastatic cancer using benzopyranone compounds

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Quick Facts
Patent No.
US 7,589,119
App. No.
12/072,011
Granted
Sep 15, 2009
Kind
B2
Abstract

This invention relates to Benzopyranone Compounds, compositions comprising a Benzopyranone Compound and methods for treating or preventing cancer or inhibiting the growth of a cancer cell or neoplastic cell comprising administering an effective amount of a Benzopyranone Compound. The Benzopyranone Compounds have the formula: or a pharmaceutically acceptable salt thereof, wherein R 1 is halogen, trifluoromethyl or C 1-6 alkyl.

Claims (15)

1. A method for treating metastatic cancer of the head, neck, eye, mouth, throat, esophagus, chest, bone, lung, colon, rectum, stomach, prostate, breast, ovary, testicle or other reproductive organ, skin, thyroid, blood, lymph node, kidney, liver, pancreas or brain, comprising administering to a patient having metastatic cancer of the head, neck, eye, mouth, throat, esophagus, chest, bone, lung, colon, rectum, stomach, prostate, breast, ovary, testicle or other reproductive organ, skin, thyroid, blood, lymph node, kidney, liver, pancreas or brain an effective amount of a compound of the formula:

or a pharmaceutically acceptable salt thereof, wherein R 1 is halogen, trifluoromethyl or C 1-6 alkyl.

2. The method of claim 1 wherein R 1 is halogen.

3. The method of claim 2 wherein halogen is fluoro.

4. The method of claim 1 wherein R 1 is C 1-6 alkyl.

5. The method of claim 4 wherein C 1-6 alkyl is methyl.

6. The method of claim 4 wherein C 1-6 alkyl is ethyl.

7. The method of claim 4 wherein C 1-6 alkyl is n-propyl.

8. The method of claim 4 wherein C 1-6 alkyl is isopropyl.

9. The method of claim 4 wherein C 1-6 alkyl is t-butyl.

10. The method of claim 1 wherein R 1 is trifluoromethyl.

11. The method of claim 1 wherein the metastatic cancer is of the brain.

12. The method of claim 1 wherein the metastatic cancer originated in the lung, breast, from an unknown primary tumor, a melanoma or colon.

13. The method of claim 12 wherein the metastatic cancer originated from small cell lung cancer.

14. The method of claim 12 wherein the metastatic cancer originated from non-small cell lung cancer.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 9, 2020
From: AMKOR TECHNOLOGY, INC.
To: AMKOR TECHNOLOGY SINGAPORE HOLDING PTE.LTD.
Reel/Frame 054067/0135 →