IP Library Granted Patent US 7,928,729
Granted Patent B2
US 7,928,729 · App. 12/188,031 · Granted Apr 19, 2011

Distortion-free magnetic resonance imaging near metallic implants

Assignee: The Board of Trustees of the Leland Stanford Junior University
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Quick Facts
Patent No.
US 7,928,729
App. No.
12/188,031
Granted
Apr 19, 2011
Kind
B2
Abstract

A method for 3D magnetic resonance imaging (MRI) with slice-direction distortion correction is provided. One or more selective cross-sections with a thickness along a first axis is excited using a RF pulse with a bandwidth, wherein a selective cross-section is either a selective slice or selective slab. A refocusing pulse is applied to form a spin echo. One or more 2D encoded image signals are acquired with readout along a second axis and phase encoding along a third axis. Slice-direction distortion is corrected by resolving the position by resolving the frequency offset.

Claims (34)

1. A method for 3D magnetic resonance imaging (MRI) with slice-direction distortion correction for distortion caused by field inhomogeneities, comprising:

a) exciting one or more selective cross-sections with a thickness along a first axis using a RF pulse with a bandwidth, wherein a selective cross-section is either a selective slice or selective slab;

b) applying a refocusing pulse to the excited one or more selective cross-sections to form a spin echo;

c) acquiring one or more 2D encoded image signals from the spin echo with readout along a second axis and phase encoding along a third axis; and

d) correcting slice-direction distortion of the one or more 2D encoded image signals by resolving the position by resolving the frequency offset.

2. The method, as recited in claim 1 , further comprising correcting readout distortion.

3. The method, as recited in claim 2 , wherein the correcting readout distortion comprises using spectral information combined with readout bandwidth and pixel size to correct in-plane distortion.

4. The method, as recited in claim 2 , wherein correcting readout distortion comprises applying view angle tilting.

5. The method, as recited in claim 4 , wherein step d comprises encoding and resolving spectral information, and using a cross-section thickness and RF bandwidth to undo slice-direction distortion.

6. The method, as recited in claim 5 , wherein the encoding is a Fourier encoding.

7. The method, as recited in claim 6 , wherein excited cross-section thickness varies to maintain a relatively constant frequency variation within the excited cross-section.

8. The method, as recited in claim 7 , further comprising measuring the frequency spectrum to predict distortion using a spectral prescan.

9. The method, as recited in claim 8 , wherein the excitation-refocusing pulses are a matched-phase pulse pair with individual pulses not necessarily having linear phase.

10. The method, as recited in claim 9 , wherein the encoding comprises using cross-section excitation profile imaging with view angle tilting.

11. The method, as recited in claim 10 , wherein the encoding of frequency offset information comprises using echo-planar spectroscopic imaging.

12. The method, as recited in claim 1 , wherein step d comprises applying additional phase encoding along the first axis to correct slice-direction distortion by resolving an actual location.

13. The method, as recited in claim 1 , wherein step d comprises encoding and resolving spectral information, and using the slice thickness and RF bandwidth to undo slice-direction distortion.

14. The method, as recited in claim 13 , wherein the encoding is a Fourier encoding.

15. The method, as recited in claim 13 , wherein the encoding comprises using slab excitation profile imaging.

16. The method, as recited in claim 13 , wherein the encoding comprises using echo-planar spectroscopic imaging.

17. The method, as recited in claim 1 , wherein excited cross-section thickness varies to maintain a relatively constant frequency variation within the excited slab.

18. The method, as recited in claim 1 , wherein the correcting slice-direction by resolving position, resolves position directly.

19. The method, as recited in claim 1 , wherein the correcting slice-direction by resolving position, resolves position indirectly.

20. An apparatus for providing 3D magnetic resonance imaging with slice-direction distortion compensation for distortion caused by field inhomogeneities, comprising:

a magnetic resonance imaging excitation and detection system; and

a controller electrically connected to the magnetic resonance imaging excitation and detection system, comprising:

a display;

at least one processor; and

non-transitory computer readable media, comprising:

computer readable code for causing the apparatus to excite one or more selective cross-sections with a thickness along a first axis using a RF pulse with a bandwidth, wherein a selective cross-section is either a selective slice or selective slab;

computer readable code for causing the apparatus to apply a refocusing pulse to the excited one or more selective cross-sections to form a spin echo;

computer readable code for causing the apparatus to acquire one or more 2D encoded image signals from the spin echo with readout along a second axis and phase encoding along a third axis;

computer readable code for causing the apparatus to correct slice-direction distortion of the one or more 2D encoded image signals by resolving the position by resolving the frequency offset; and

computer readable code for causing the apparatus to display a 3D magnetic resonance image with slice-direction distortion correction on the display.

Assignments (3)
CONFIRMATORY LICENSE Recorded Jul 28, 2010
From: STANFORD UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 024756/0789 →
CONFIRMATORY LICENSE Recorded Feb 23, 2009
From: STANFORD UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 022294/0502 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 12, 2008
From: HARGREAVES, BRIAN A.; LU, WENMIAO; PAULY, JOHN M.; GOLD, GARRY E.; PAULY, KIM B.
To: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Reel/Frame 021375/0727 →
Continuity (1)
Related Publication 20100033179A1 · Feb 11, 2010