IP Library › Granted Patent US 7,892,804
Granted Patent B2
US 7,892,804 · App. 12/235,253 · Granted Feb 22, 2011

Arabinitol dehydrogenases from

Assignees: The Board of Trustees of the University of Illinois; Biotechnology Research and Development Corporation
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Quick Facts
Patent No.
US 7,892,804
App. No.
12/235,253
Granted
Feb 22, 2011
Kind
B2
Abstract

Stable and active arabinitol dehydrogenases (LAD) from Neurospora crassa and mutants thereof are disclosed. Arabinitol dehydrogenases are useful in the production of xylitol and ethanol from an arabinose containing substrate. Recombinant and heterologously expressed arabinitol dehydrogenases are useful in converting biomass into biofuels and other industrial food products.

Claims (7)

1. A purified arabinitol dehydrogenase wherein the arabinitol dehydrogenase comprises a tetramer of a polypeptide, where the polypeptide comprises an amino acid sequence that is at least 95% similar to SEQ ID NO: 1.

2. The arabinitol dehydrogenase of claim 1 is recombinant.

3. The arabinitol dehydrogenase of claim 1 is heterologously expressed.

4. The arabinitol dehydrogenase of claim 1 is about 95% pure.

5. The arabinitol dehydrogenase of claim 1 is purified from a heterologous host selected from the group consisting of bacteria, yeast, and plants.

6. The purified arabinitol dehydrogenase of claim 1 is a fusion protein.

7. The purified arabinitol dehydrogenase of claim 1 further comprises a purification tag.

Assignments (3)
SECURITY AGREEMENT Recorded Apr 4, 2013
From: ZUCHEM, INC.
To: 2120 INVESTMENTS, INC.
Reel/Frame 030156/0134 →
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS ASSIGNS AN UNDIVIDED 50% SHARE OF ITS ENTIRE RIGHT, TITLE, AND INTEREST IN THE APPLICATION TO BIOTECHNOLOGY RESEARCH AND DEVELOPMENT CORPORATION. Recorded Nov 11, 2008
From: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
To: BIOTECHNOLOGY RESEARCH AND DEVELOPMENT CORPORATION
Reel/Frame 021813/0743 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 7, 2008
From: ZHAO, HUIMIN; SULLIVAN, RYAN
To: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
Reel/Frame 021803/0260 →
Continuity (2)
Provisional Application 60975023 · Sep 25, 2007
Related Publication 20090081734A1 · Mar 26, 2009