IP Library › Granted Patent US 7,973,075
Granted Patent B2
US 7,973,075 · App. 12/243,281 · Granted Jul 5, 2011

Kainate receptor-selective epimeric analogs of dysiherbaine

Assignee: Northwestern University
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Quick Facts
Patent No.
US 7,973,075
App. No.
12/243,281
Granted
Jul 5, 2011
Kind
B2
Abstract

Disclosed are compounds, pharmaceutical compositions, methods of treatment, and methods for selectively antagonizing a GluR5 receptor, a GluR6 receptor, or both receptors. The pharmaceutical compositions include and the methods utilize compounds that are analogs and stereoisomers of dysiherbaine and neodysiherbaine which have specificity for kainate receptors.

Claims (7)

1. A pharmaceutical composition comprising:

(a) a compound having the formula

and

(b) one or more pharmaceutically acceptable carriers, diluents, or excipients.

2. The composition of claim 1 , wherein the composition is suitable for administration to a human.

3. The composition of claim 1 , wherein the composition is suitable for oral administration.

4. The composition of claim 1 , wherein the composition is suitable for transdermal administration.

Assignments (3)
CONFIRMATORY LICENSE Recorded Jul 15, 2010
From: NORTHWESTERN UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 024694/0028 →
EXECUTIVE ORDER 9424, CONFIRMATORY LICENSE Recorded Feb 19, 2009
From: NORTHWESTERN UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 022282/0539 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 20, 2009
From: SWANSON, GEOFFREY T.; LASH, LEANNE
To: NORTHWESTERN UNIVERSITY
Reel/Frame 022129/0208 →
Continuity (2)
Provisional Application 60976889 · Oct 2, 2007
Related Publication 20090118358A1 · May 7, 2009