Murine calicivirus
The invention disclosed herein relates to a newly discovered murine norovirus, and compositions and methods related thereto.
1. An isolated polypeptide comprising an amino acid sequence at least 80% identical to SEQ ID NO: 3.
2. An isolated polypeptide in accordance with claim 1 , wherein the sequence is at least 95% identical to SEQ ID NO: 3.
3. An isolated polypeptide in accordance with claim 1 , wherein the polypeptide consists of the amino acid sequence of SEQ ID NO: 3.
4. An assay surface comprising an immunosorbent surface and at least one polypeptide immobilized thereupon comprising an amino acid sequence that is at least 80% identical to SEQ ID NO: 3.
5. An assay surface in accordance with claim 4 , wherein the at least one polypeptide is at least 95% identical to SEQ ID NO: 3.
6. An assay surface in accordance with claim 4 , wherein the at least one polypeptide consists of the amino acid sequence of SEQ ID NO: 3.
7. An assay surface in accordance with claim 4 , wherein the immunosorbent surface is an ELISA plate.
8. A kit comprising the assay surface of claim 4 , and at least one reagent for detecting binding of the polypeptide that comprises a sequence at least 80% identical to SEQ ID NO: 3 with an antibody if present in a sample.
9. A kit comprising the assay surface of claim 5 , and at least one reagent for detecting binding of the polypeptide that has a sequence at least 95% identical to SEQ ID NO: 3 with an antibody if present in a sample.
10. A kit in accordance with claim 8 , wherein the kit further comprises an anti-mouse immunoglobulin.
11. A kit in accordance with claim 10 , wherein the anti-mouse immunoglobulin is an enzyme-conjugated anti-mouse immunoglobulin.