IP Library Granted Patent US 8,628,770
Granted Patent B2
US 8,628,770 · App. 12/259,575 · Granted Jan 14, 2014

Slimming cosmetic composition containing a substance inducing the production of IL-6

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Quick Facts
Patent No.
US 8,628,770
App. No.
12/259,575
Granted
Jan 14, 2014
Kind
B2
Abstract

This invention relates to a slimming cosmetic composition containing at least one compound inducing the production of IL-6 by the adipocytes in the form of a mixture with an NPY antagonist and/or an α 2 antagonist and with an excipient for a cosmetic preparation.

Claims (11)

1. A slimming cosmetic composition comprising three components:

1) a neuropeptide Y (NPY) antagonist component purified from an extract obtained by fermentation by the Streptomyces sp. strain deposited at the C.N.C.M. of Institut Pasteur under the number I-1132;

2) an α 2 antagonist component purified from an extract obtained by fermentation by the Bacillus licheniformis strain deposited at the C.N.C.M. of Institut Pasteur under the number I-1778; and

3) a component inducing production of interleukin-6 (IL-6) by adipocytes that is purified from an extract obtained by fermentation by the Rhodotorula sp. strain deposited at the C.N.C.M. of Institut Pasteur under the number I-1844,

said components in a mixture along with an excipient for cosmetic preparations.

2. A slimming cosmetic composition for topical application comprising:

1) a neuropeptide Y (NPY) antagonist purified from an extract obtained by fermentation by the Streptomyces sp. strain deposited at the C.N.C.M. of Institut Pasteur under the number I-1132;

2) an α 2 antagonist purified from an extract obtained by fermentation by the Bacillus licheniformis strain deposited at the C.N.C.M. of Institut Pasteur under the number I-1778;

3) an inducer of the production of IL-6 by adipocytes, said inducer purified from an extract obtained by fermentation by the Rhodotorula sp. strain deposited at the C.N.C.M. of Institut Pasteur under the number I-1844; and

4) a cosmetically acceptable excipient.

3. A method for regulating lipolysis/lipogenesis in the skin comprising administering to a subject a composition of claim 1 or 2 .

Assignments (3)
CHANGE OF NAME Recorded Jun 20, 2012
From: SANOFI-AVENTIS
To: SANOFI
Reel/Frame 028413/0927 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 9, 2012
From: CASELLAS, PIERRE; DEROCQ, JEAN-MARIE; GUESNET, JOELLE
To: SANOFI-SYNTHELABO
Reel/Frame 028180/0959 →
CHANGE OF NAME Recorded May 9, 2012
From: SANOFI-SYNTHELABO
To: SANOFI-AVENTIS
Reel/Frame 028184/0805 →